Support for COPD patients after hospital discharge

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial focuses on providing supported rescue packs to patients with chronic obstructive pulmonary disease (COPD) who have recently been discharged from the hospital after experiencing exacerbations. The rescue packs include a course of prednisolone and antibiotics, along with a basic management plan to help patients manage their condition at home. The study aims to reduce the high rates of readmission and improve self-management during the critical 90-day post-discharge period. By evaluating the effectiveness of these packs, the trial seeks to enhance patient outcomes and reduce healthcare costs associated with COPD exacerbations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 40 years
* Individuals admitted to hospital with COPD exacerbation who have recently been discharged (discharged from ongoing support from secondary care team which includes hospital and virtual wards). Admission is defined as an episode in which a patient with an exacerbation of COPD is admitted to a ward and has stayed in hospital for 4 hours or more, including Emergency Medicine Centres, Medical Admission Units, Clinical Decision Units, short stay wards or similar but excludes patients treated transiently before being discharged from Emergency Department.
* Ability to provide written informed consent

Exclusion Criteria:

* Individuals who require invasive ventilation during the hospital admission
* Patients who have an expected survival of less than 90 days
* Patients with signs of new consolidation on chest X-ray (if available).
* Individuals who have been discharged to a residential or nursing home to residential or nursing home.
* Individuals who are unable to manage a supported self-management plan.
* Individuals with no access to telephone.
* Individuals who are already taking part in an interventional trial.
* Previous participation in the RAPID trial.

Where it's running

• Barnsley Hospital NHS Foundation Trust
  Barnsley, United Kingdom Recruiting
• University Hospitals Sussex NHS Foundation Trust
  Brighton, United Kingdom Recruiting
• County Durham and Darlington NHS Foundation Trust
  Durham, United Kingdom Recruiting
• East Suffolk and North Essex Foundation Trust
  Ipswich, United Kingdom Recruiting
• Nottingham University Hospitals Trust
  Nottingham, United Kingdom Recruiting
• Oxford University Hospitals NHS Foundation Trust
  Oxford, United Kingdom Recruiting

Study contacts

• Principal investigator: Mona Bafadhel, Professor — King's College London
• Study coordinator: Mona Bafadhel, Professor
• Email: mona.bafadhel@kcl.ac.uk
• Phone: +44207 848 0606

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.