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Support for COPD patients after hospital discharge

Supported Rescue Packs Post-discharge in Chronic Obstructive Pulmonary Disease: An Open-label Multicenter Randomised Controlled Trial

Phase 3 Interventional Guy's and St Thomas' NHS Foundation Trust · NCT06347536

This study tests whether giving COPD patients special rescue packs with medication and a management plan after they leave the hospital can help them stay healthier and avoid going back to the hospital.

Quick facts

PhasePhase 3
Study typeInterventional
Enrollment1400 (estimated)
Ages40 Years and up
SexAll
SponsorGuy's and St Thomas' NHS Foundation Trust Academic / other
Locations34 sites (Barnsley and 33 other locations)
Trial IDNCT06347536 on ClinicalTrials.gov

What this trial studies

This clinical trial focuses on providing supported rescue packs to patients with chronic obstructive pulmonary disease (COPD) who have recently been discharged from the hospital after experiencing exacerbations. The rescue packs include a course of prednisolone and antibiotics, along with a basic management plan to help patients manage their condition at home. The study aims to reduce the high rates of readmission and improve self-management during the critical 90-day post-discharge period. By evaluating the effectiveness of these packs, the trial seeks to enhance patient outcomes and reduce healthcare costs associated with COPD exacerbations.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 40 and older who have been hospitalized for a COPD exacerbation and are being discharged from secondary care.

Not a fit: Patients requiring invasive ventilation during their hospital admission or those with a life expectancy of less than 90 days may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce hospital readmissions and improve the quality of life for COPD patients.

How similar studies have performed: Previous studies have indicated that interventions aimed at managing COPD exacerbations post-discharge can lead to improved patient outcomes, suggesting this approach has potential based on existing evidence.

Eligibility criteria

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Age ≥ 40 years
* Individuals admitted to hospital with COPD exacerbation who have recently been discharged (discharged from ongoing support from secondary care team which includes hospital and virtual wards). Admission is defined as an episode in which a patient with an exacerbation of COPD is admitted to a ward and has stayed in hospital for 4 hours or more, including Emergency Medicine Centres, Medical Admission Units, Clinical Decision Units, short stay wards or similar but excludes patients treated transiently before being discharged from Emergency Department.
* Ability to provide written informed consent

Exclusion Criteria:

* Individuals who require invasive ventilation during the hospital admission
* Patients who have an expected survival of less than 90 days
* Patients with signs of new consolidation on chest X-ray (if available).
* Individuals who have been discharged to a residential or nursing home to residential or nursing home.
* Individuals who are unable to manage a supported self-management plan.
* Individuals with no access to telephone.
* Individuals who are already taking part in an interventional trial.
* Previous participation in the RAPID trial.

Where this trial is running

Barnsley and 33 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov → Find more trials like this →
Conditions COPDCOPD Exacerbationexacerbationhospital admissionrescue packsself-management support
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.