Improving oral care to prevent pneumonia in COPD patients in the ICU
Official title: Routine Oral Care Versus Chlorhexidine Oral Care on Incidence of Nosocomial Pneumonia and Oral Health Among Critically Ill Non-intubated Patients With COPD
Run by Assiut University · NCT06691399 · Data updated 2026-11-12
This study is testing if better oral care can help prevent pneumonia in COPD patients who are in the ICU.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut) |
| Status | Recruiting |
| Started | October 1, 2024 |
| Main results expected | April 1, 2025 |
| Study ends | June 1, 2025 |
| Registry record updated | November 15, 2024 |
| Trial ID | NCT06691399 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are COPD patients who are admitted to the ICU with acute exacerbations and require noninvasive ventilatory support.
✕Probably not a fit
Patients with end-stage organ failure or those who refuse to participate may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the impact of enhanced oral care on the prevention of nosocomial pneumonia in patients with Chronic Obstructive Pulmonary Disease (COPD) who are admitted to the ICU. It focuses on the relationship between poor dental hygiene and the colonization of respiratory pathogens in the oral cavity, which can lead to pneumonia. By implementing oral care interventions, the study aims to reduce the incidence of pneumonia and improve patient outcomes in critical care settings. The methodology includes assessing the oral hygiene practices and monitoring the development of pneumonia in participating patients.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of pneumonia in ICU patients with COPD, leading to improved survival rates and reduced healthcare costs.
How similar studies have gone: While the specific approach of this study may be novel, previous studies have indicated that improving oral hygiene can reduce the risk of pneumonia in ICU settings.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients diagnosed as COPD * admitted to ICU with acute exacerbation * need for noninvasive ventilatory support including noninvasive ventilation anf high flow nasal cannula Exclusion Criteria: * patients refusing to participate * End stage organ failure (Heart Failure, Liver cell failure and/or Renal failure
Where it's running
-
Faculty of Medicine, Assiut University
Asyut, Egypt Recruiting
Study contacts
- Principal investigator: Waleed MD Gamal Elddin Khaleel, Ass. Prof. — Assiut University
- Study coordinator: Waleed MD Gamal Elddin Khaleel, Ass. Prof.
- Email: waleed_gamal@aun.edu.eg
- Phone: +201006519722
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Early detection of COPD flares with a home monitoring device
A home-monitoring device called RespirAI is being tested to see if it can alert adults with COPD about coming flare-ups before they happen.
-
High-intensity resistance training after a COPD exacerbation
This project tests whether a short program of high-load, low-repetition leg-strength training helps people recovering from a COPD flare rebuild strength and exercise tolerance with less breathlessness than standard endurance exercise.
-
Support for COPD patients after hospital discharge
This study tests whether giving COPD patients special rescue packs with medication and a management plan after they leave the hospital can help them stay healthier and avoid going back to the hospital.
-
Observing patients with severe COPD exacerbations in the ICU
This study looks at patients with severe COPD flare-ups in the ICU to learn more about their health, treatments, and chances of recovery.
-
Effects of CPAP on COPD and Sleep Apnea Overlap Syndrome
This study is testing if using a CPAP machine can help people with both COPD and sleep apnea feel better and reduce health problems over a year.
-
Comparing new nasal interface with standard cannula for COPD patients
This study is testing a new type of nasal breathing device against a standard one to see which helps people with COPD feel better during a flare-up.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.