Improving oral care to prevent pneumonia in COPD patients in the ICU
Routine Oral Care Versus Chlorhexidine Oral Care on Incidence of Nosocomial Pneumonia and Oral Health Among Critically Ill Non-intubated Patients With COPD
This study is testing if better oral care can help prevent pneumonia in COPD patients who are in the ICU.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut) |
| Trial ID | NCT06691399 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of enhanced oral care on the prevention of nosocomial pneumonia in patients with Chronic Obstructive Pulmonary Disease (COPD) who are admitted to the ICU. It focuses on the relationship between poor dental hygiene and the colonization of respiratory pathogens in the oral cavity, which can lead to pneumonia. By implementing oral care interventions, the study aims to reduce the incidence of pneumonia and improve patient outcomes in critical care settings. The methodology includes assessing the oral hygiene practices and monitoring the development of pneumonia in participating patients.
Who should consider this trial
Good fit: Ideal candidates for this study are COPD patients who are admitted to the ICU with acute exacerbations and require noninvasive ventilatory support.
Not a fit: Patients with end-stage organ failure or those who refuse to participate may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of pneumonia in ICU patients with COPD, leading to improved survival rates and reduced healthcare costs.
How similar studies have performed: While the specific approach of this study may be novel, previous studies have indicated that improving oral hygiene can reduce the risk of pneumonia in ICU settings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients diagnosed as COPD * admitted to ICU with acute exacerbation * need for noninvasive ventilatory support including noninvasive ventilation anf high flow nasal cannula Exclusion Criteria: * patients refusing to participate * End stage organ failure (Heart Failure, Liver cell failure and/or Renal failure
Where this trial is running
Asyut
- Faculty of Medicine, Assiut University — Asyut, Egypt (Recruiting)
Study contacts
- Principal investigator: Waleed MD Gamal Elddin Khaleel, Ass. Prof. — Assiut University
- Study coordinator: Waleed MD Gamal Elddin Khaleel, Ass. Prof.
- Email: waleed_gamal@aun.edu.eg
- Phone: +201006519722
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.