Home-based pulmonary rehabilitation for severe COPD management

The Effect of Close Follow-Up Home Based Pulmonary Rehabilitation on Exacerbation Frequency and Hospital Admission in Severe COPD Cases

NA · Saglik Bilimleri Universitesi · NCT05738720

This study is testing if a home-based rehabilitation program can help people with severe COPD have fewer flare-ups and hospital visits while improving their breathing and strength.

Quick facts

PhaseNA
Study typeInterventional
Enrollment24 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorSaglik Bilimleri Universitesi (other)
Locations1 site (Istanbul)
Trial IDNCT05738720 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of home-based pulmonary rehabilitation in reducing exacerbations and hospital admissions for patients with severe COPD. Participants will be randomly assigned to either a homespirometer group, which will utilize a home spirometer for weekly monitoring, or a control group. Both groups will engage in breathing exercises, aerobic activities, and muscle strengthening. Evaluations will occur at baseline and at 3, 6, and 12 months to assess exercise capacity, muscle strength, and frequency of disease exacerbations.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-75 with a diagnosis of COPD stages C and D who experience dyspnea on exertion and are stable without recent exacerbations.

Not a fit: Patients with severe comorbidities or those who have participated in a pulmonary rehabilitation program in the past year may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce hospital admissions and improve the quality of life for patients with severe COPD.

How similar studies have performed: Previous studies have shown that pulmonary rehabilitation can effectively reduce exacerbations and hospitalizations in COPD patients, indicating a promising approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Being between the ages of 18-75

* Having a diagnosis of COPD stages C and D diagnosed according to the GOLD (Global Initiative for Chronic Obstructive Lung Disease) clinical diagnostic criteria
* Presence of dyspnea on exertion
* Stable clinical condition at the time of inclusion without infection or exacerbation in the previous 4 weeks
* Having the ability to use a smart phone and spirometer after training

Exclusion Criteria:

* Patients with severe comorbid diseases, unstable coronary artery disease, collagen vascular diseases and needing high flow oxygen therapy (˃ 3-4 L \\min).
* A history of effort-related syncope or any comorbidity (such as severe orthopedic or neurological deficits or unstable heart disease) that precludes exercise training.
* Participation in a pulmonary rehabilitation program within the past 12 months.

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: COPD Exacerbation, copd exacerbation, pulmonary rehabilitation, spirometry, hospital admission

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.