Drug or treatment

Axatilimab clinical trials

• 9Clinical trials
• 21Countries

Newest trials

All recruiting trials (9)

• Axatilimab plus ruxolitinib for people with myelofibrosis or CMML

  This trial tests whether adding axatilimab, an antibody that targets CSF1R, to ruxolitinib can help control disease and symptoms in adults with myelofibrosis or chronic myelomonocytic leukemia (CMML).

  Recruiting Phase 1/2 M.D. Anderson Cancer Center · Houston, Texas · NCT07128381

• Axatilimab versus best available therapy for children with chronic graft-versus-host disease after two or more prior treatments

  This trial will test axatilimab against the best available treatments in children aged 2–17 whose chronic graft-versus-host disease has not responded to at least two prior systemic therapies.

  Recruiting at 34 sites Phase 2 Incyte Corporation · Duarte, California and 40 other locations · NCT07124078

• Axatilimab to treat skin thickening (sclerosis) from chronic graft‑versus‑host disease

  This trial tests whether axatilimab can improve or stop worsening skin thickening (sclerosis) in adults with chronic graft‑versus‑host disease after a donor stem cell transplant.

  Recruiting at 2 sites Phase 2 Fred Hutchinson Cancer Center · Tampa, Florida and 2 other locations · NCT07011810

• Combination treatment for chronic Graft-versus-Host Disease

  This study is testing a new combination treatment with Axatilimab and light therapy to see if it helps people with chronic Graft-versus-Host Disease who haven't responded well to other treatments.

  Recruiting at 3 sites Phase 2 University of Miami · San Francisco, California and 2 other locations · NCT06663722

• Evaluating axatilimab and corticosteroids for treating chronic graft-versus-host disease

  This study is testing if adding a new drug called axatilimab to standard steroids can help people aged 12 and older who have recently developed moderate to severe chronic graft-versus-host disease feel better.

  Recruiting at 131 sites Phase 3 Incyte Corporation · Birmingham, Alabama and 130 other locations · NCT06585774

• Axatilimab with or without azacitidine for adults with advanced myeloproliferative neoplasms or high‑risk CMML

  This trial tests whether the antibody axatilimab, alone or together with the chemotherapy azacitidine, can help adults with advanced‑phase myeloproliferative neoplasms, MPN/MDS overlap, or high‑risk chronic myelomonocytic leukemia (CMML).

  Recruiting at 2 sites Phase 1/2 Ohio State University Comprehensive Cancer Center · Columbus, Ohio and 1 other locations · NCT06523556

• Testing axatilimab with olaparib for advanced HER2-negative breast cancer with specific gene mutations

  This study is testing a new drug called axatilimab combined with olaparib to see if it helps people with advanced HER2-negative breast cancer who have specific gene mutations.

  Recruiting at 2 sites Phase 1 Dana-Farber Cancer Institute · Boston, Massachusetts and 1 other locations · NCT06488378

• Combining axatilimab, retifanlimab, and paclitaxel for advanced solid tumors

  This study is testing a new combination of three medications to see if they can help people with advanced solid tumors feel better and improve their treatment outcomes.

  Recruiting Phase 1/2 OHSU Knight Cancer Institute · Portland, Oregon · NCT06320405

• Axatilimab at Three Doses for Chronic GVHD

  This study tests three dose levels of axatilimab in people 2 years and older whose chronic graft-versus-host disease has not responded to at least two prior treatments.

  Recruiting at 13 sites Phase 2 Syndax Pharmaceuticals · Birmingham, Alabama and 120 other locations · NCT04710576

Quick answers

How many clinical trials of Axatilimab are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 21 countries. The most sites are in United States (9 trials), Germany (3 trials), Italy (3 trials), Spain (3 trials), United Kingdom (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1/2: 3, Phase 3: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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