Condition

Chemotherapy Induced Peripheral Neuropathy (CIPN) clinical trials and research

• 16Clinical trials
• 11Countries

Newest Chemotherapy Induced Peripheral Neuropathy (CIPN) clinical trials

All recruiting trials (16)

• Cryotherapy during weekly paclitaxel to reduce chemotherapy-induced numbness and tingling

  This study tests whether applying cryotherapy to hands and feet during weekly paclitaxel helps prevent CIPN in women with breast cancer.

  Recruiting at 3 sites Azienda Sanitaria dell'Alto Adige · Bolzano, Bolzano and 3 other locations · NCT07780955

• Electroacupuncture and Exercise for Chemotherapy-Induced Peripheral Neuropathy

  This study tests whether adding a structured exercise program to electroacupuncture helps cancer survivors with CIPN more than electroacupuncture alone.

  Recruiting at 2 sites Show Chwan Memorial Hospital · Changhua, Changhua and 1 other locations · NCT07700901

• Virtual exercise program to help with chemotherapy-induced nerve symptoms

  This trial tests whether a remote, personalized exercise program (EX-CIPN) can reduce CIPN symptoms and related disability in cancer survivors who have persistent neuropathy after chemotherapy, compared with usual care.

  Recruiting Phase 3 University Health Network, Toronto · Toronto, Ontario · NCT07481149

• Acupuncture and compression to prevent chemotherapy-induced nerve damage in breast cancer

  This trial will test whether wearing compression garments and/or receiving acupuncture during taxane chemotherapy can prevent chemotherapy-induced peripheral neuropathy in adults with early-stage breast cancer.

  Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT07377279

• PEA and Scutellaria combined with exercise for chemotherapy-related nerve pain

  This trial will see if taking PEA and Scutellaria together with therapeutic exercise helps adults who have nerve pain after chemotherapy.

  Recruiting University of Palermo · Palermo, Italia · NCT07352514

• Assessing Functional Impairments in CIPN Patients

  This study tests how CIPN affects daily function by using functional tests alongside patient self-reports to see how well the tests reflect everyday difficulties.

  Recruiting Paracelsus Medical University · Salzburg · NCT07315334

• Closed-loop spinal cord stimulation for painful chemotherapy-induced peripheral neuropathy

  This observational project will try closed-loop spinal cord stimulation to reduce neuropathic pain in adults who developed peripheral neuropathy after chemotherapy.

  Recruiting at 5 sites Rijnstate Hospital · Arnhem and 4 other locations · NCT07304401

• Lilac low-pressure glove and boot to protect nerves during chemotherapy

  Tests if wearing Lilac low-pressure gloves and boots during certain oxaliplatin- or paclitaxel-based chemotherapy can lessen peripheral nerve damage in adults.

  Recruiting at 17 sites Luminate Medical, Inc. · Poway, California and 17 other locations · NCT07142304

• Great toe strength in people with chemotherapy-induced peripheral neuropathy

  This research tests whether a small device called ToeScale can measure great toe strength in adults with CIPN and in matched healthy adults.

  Recruiting University of Florida · Gainesville, Florida · NCT07009717

• GM1 to prevent nerve damage from albumin-paclitaxel in breast cancer patients.

  This trial will test whether GM1 can prevent peripheral nerve damage in adults with breast cancer who are receiving albumin-paclitaxel chemotherapy.

  Recruiting Phase 3 Qilu Pharmaceutical Co., Ltd. · Beijing · NCT06994507

• Cold salt-water foot baths to prevent paclitaxel-related nerve damage

  This study tests whether taking cold salt-water or plain cold-water foot baths during paclitaxel chemotherapy can prevent or reduce chemotherapy-related peripheral nerve damage in women with breast cancer.

  Recruiting Istanbul Topkapi University · Istanbul, Uskudar · NCT06964802

• Personalized exercise to prevent chemotherapy-related nerve damage

  This study will see if a tailored exercise program can prevent nerve-related symptoms in adults getting taxane- or platinum-based chemotherapy for breast, gynecological, or colon cancer.

  Recruiting at 2 sites Universiteit Antwerpen · Edegem and 1 other locations · NCT06962579

• Using electroacupuncture to help with chemotherapy-induced nerve pain

  This study is testing if electroacupuncture can help reduce nerve pain from chemotherapy in patients who are struggling with symptoms like numbness and tingling.

  Recruiting Zhongnan Hospital · Wuhan, Hubei · NCT06858709

• Examining gut microbiome profiles in patients with chemotherapy-induced neuropathy

  This study is trying to see if the gut bacteria of patients getting ozone therapy for chemotherapy-related nerve pain can help explain why some feel better while others don’t.

  Recruiting Phase 2/3 Hospital Universitario de Gran Canaria Doctor Negrín · Las Palmas, Las Palmas · NCT06799351

• Ozone therapy for numbness and tingling from chemotherapy

  This study is testing if ozone therapy can help reduce numbness and tingling in cancer patients who have nerve damage from chemotherapy.

  Recruiting Phase 2/3 Hospital Universitario de Gran Canaria Doctor Negrín · Las Palmas, Las Palmas · NCT06706544

• Sensory testing to guide medication choice for painful peripheral neuropathy

  This will try to see if sensory testing can predict which people with painful peripheral neuropathy get more pain relief from duloxetine or pregabalin than from placebo.

  Recruiting at 7 sites Phase 2 University of Rochester · Boston, Massachusetts and 6 other locations · NCT06614322

Related topics

Quick answers

How many Chemotherapy Induced Peripheral Neuropathy (CIPN) clinical trials are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in China (3 trials), United States (3 trials), Spain (2 trials), Italy (2 trials), Turkey (Türkiye) (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 2, Phase 3: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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