Condition

CIPN - Chemotherapy-Induced Peripheral Neuropathy clinical trials and research

• 8Clinical trials
• 6Countries

Newest CIPN - Chemotherapy-Induced Peripheral Neuropathy clinical trials

All recruiting trials (8)

• Cryotherapy during weekly paclitaxel to reduce chemotherapy-induced numbness and tingling

  This study tests whether applying cryotherapy to hands and feet during weekly paclitaxel helps prevent CIPN in women with breast cancer.

  Recruiting at 3 sites Azienda Sanitaria dell'Alto Adige · Bolzano, Bolzano and 3 other locations · NCT07780955

• Hyperbaric oxygen therapy for nab-paclitaxel-induced neuropathy in breast cancer

  This study tests whether hyperbaric oxygen therapy can help relieve neuropathy from nab-paclitaxel in adult women with breast cancer who have finished chemotherapy.

  Recruiting at 2 sites Phase 2/3 Guangdong Provincial People's Hospital · Guangzhou, Guangdong and 1 other locations · NCT07410169

• Scrambler Therapy for chemotherapy-related nerve pain (CIPN).

  Researchers will try Scrambler Therapy, a non-drug electrical treatment, to reduce pain and numbness in people with long-lasting chemotherapy-induced peripheral neuropathy.

  Recruiting Case Comprehensive Cancer Center · Cleveland, Ohio · NCT07219472

• VMD-3866 topical gel for chemotherapy-induced nerve pain

  This trial will test whether a non-opioid topical gel called VMD-3866 can reduce pain in adults with chemotherapy-induced peripheral neuropathy.

  Recruiting Phase 2 VM Therapeutics LLC · London, UK · NCT07072468

• Cryocompression to prevent taxane-induced nerve damage in the arms and legs.

  This study tests whether cooling and pressure applied to the arms and legs during taxane chemotherapy can prevent or reduce numbness, pain, or weakness from peripheral neuropathy in adults with breast or gynecologic cancer.

  Recruiting Dana-Farber Cancer Institute · Boston, Massachusetts · NCT07064798

• Using Scrambler Therapy with Duloxetine for Chemotherapy-Induced Peripheral Neuropathy

  This study is testing if combining Scrambler therapy with duloxetine can help reduce pain in people who have chemotherapy-induced nerve damage.

  Recruiting Phase 2 Fox Chase Cancer Center · Philadelphia, Pennsylvania · NCT06914557

• Explicit Sensory Retraining for Chemo-Induced Peripheral Neuropathy

  This study tests whether three sessions of explicit sensory retraining for the legs, compared with usual care, can help reduce symptoms and improve function in adults with CIPN after chemotherapy.

  Recruiting Assaf-Harofeh Medical Center · Tzrifin · NCT06724861

• Using cryotherapy to prevent nerve damage from breast cancer chemotherapy

  This study is testing whether using cold therapy during chemotherapy can help prevent nerve damage in women with early-stage breast cancer.

  Recruiting Copenhagen University Hospital, Rigshospitalet · Copenhagen · NCT05928429

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Quick answers

How many CIPN - Chemotherapy-Induced Peripheral Neuropathy clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (3 trials), United Kingdom (1 trial), Israel (1 trial), Denmark (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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