Condition

Apnea of Prematurity clinical trials and research

• 11Clinical trials
• 3NIH research projects
• 9Countries

Newest Apnea of Prematurity clinical trials

All recruiting trials (11)

• Wireless MicroPremVitals Button Sensor for the NICU

  This study tests a tiny wireless sensor system to monitor heart rate, oxygen, and temperature in extremely preterm babies in the NICU to see if it works safely without wires.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07732257

• Caffeine in pregnancy: how the mother and baby handle it during delivery

  This study tests how caffeine is processed in pregnant people and how much reaches the baby when given shortly before delivery.

  Recruiting Phase 1 Indiana University · Indianapolis, Indiana · NCT07570121

• Detection of Respiratory Events in Extremely Preterm Infants Using Acoustic Monitoring

  A new acoustic monitoring approach is being tested to detect breathing problems in very preterm babies to help NICU teams spot and manage apnea and related events.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07552025

• PIMUN to reduce low-oxygen episodes in preterm infants

  We will test whether PIMUN, a soft garment that gives gentle pulsatile dorsal stimulation, can reduce low-oxygen (SpO2 <90%) episodes in preterm infants born at 24–34 weeks who have apnea of prematurity.

  Recruiting Pontificia Universidad Catolica de Chile · Santiago, Santiago Metropolitan and 1 other locations · NCT07396103

• Using EEG to time stopping caffeine in premature infants

  This study will see if EEG brain recordings can help doctors decide when to stop caffeine treatment in preterm infants so apnea does not come back.

  Recruiting Uludag University · Bursa · NCT07324941

• Caffeine citrate after discharge for moderately preterm infants at risk of apnea

  This trial tests whether continuing caffeine citrate after hospital discharge reduces apnea-related healthcare visits and improves development at 12 months in moderately preterm infants, compared to a placebo.

  Recruiting Phase 4 University of Alabama at Birmingham · Lusaka, Lusaka Province · NCT06518603

• Caffeine citrate loading dose before extubation in preterm infants

  This study tests if giving a dose of caffeine to preterm babies before they are taken off the ventilator can help them breathe better and stay off the machine successfully.

  Recruiting at 2 sites Phase 4 Semmelweis University · Budapest and 1 other locations · NCT06401083

• Novel incubator pad for treating apnea in premature infants

  This study is testing a new incubator pad that uses gentle vibrations to help preterm infants with apnea breathe better and need less medical support.

  Recruiting at 2 sites Tufts Medical Center · Birmingham, Alabama and 1 other locations · NCT06374147

• Observational study on a new wearable device for diagnosing sleep breathing issues in children

  This study is testing a new wearable device to see if it can help doctors better diagnose breathing problems during sleep in children, especially those who find traditional tests hard to use.

  Recruiting NHS Greater Clyde and Glasgow · Glasgow, Glasgow City and 1 other locations · NCT06292299

• Using womb sounds to help preterm infants breathe better

  This study tests if playing womb sounds can help preterm infants breathe better by supporting their brain development during a crucial time.

  Recruiting Case Western Reserve University · Cleveland, Ohio · NCT05298748

• Doxapram treatment for preterm infants with breathing issues

  This study is testing if doxapram can help preterm infants with breathing problems avoid serious complications and reduce the need for breathing machines.

  Recruiting at 18 sites Phase 3 Erasmus Medical Center · Brussels, Avenaue Hippocrate 10 and 23 other locations · NCT04430790

NIH-funded research (3)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Continuous monitor to better detect and classify apnea in premature newborns

  A small multimodal breathing monitor plus smart software designed to automatically tell what kind of apnea premature babies are having.

  NIH research Makani Science, INC. · Irvine, United States · NIH-11318949

• A new incubator pad to help premature infants with breathing problems.

  This study is testing a new kind of pad that gently vibrates to help premature babies who have trouble breathing, with the hope of making them feel better and reducing their breathing problems.

  NIH research Prapela, INC. · Portland, UNITED STATES · NIH-11047736

• A new monitoring system for detecting breathing issues in premature babies

  This study is working on a new way to keep an eye on premature babies to better spot and understand their breathing pauses, helping doctors provide safer and better care for these little ones.

  NIH research Makani Science, INC. · Irvine, United States · NIH-11041360

Related topics

Quick answers

How many Apnea of Prematurity clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (3 trials), Canada (3 trials), Belgium (1 trial), Netherlands (1 trial), Hungary (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Phase 3: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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