A new monitoring system for detecting breathing issues in premature babies
Official title: Continuous Respiratory Monitoring Platform for Classifying Apnea of Prematurity
Funded at Makani Science, INC. · NIH-11041360 · Data updated 2026-11-12
This study is working on a new way to keep an eye on premature babies to better spot and understand their breathing pauses, helping doctors provide safer and better care for these little ones.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Makani Science, INC. NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | April 9, 2025 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $371,021 |
| NIH project number | 1R61HL177500-01 |
| Project ID | NIH-11041360 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are premature newborns, particularly those under 4 weeks old, who are at risk for apnea of prematurity.
✕Less likely to help
Patients who are not premature or those over 4 weeks old may not benefit from this research.
What this research studies
This research focuses on developing a continuous monitoring platform specifically designed to classify apnea of prematurity (AOP) in newborns. The project aims to create a multimodal monitoring system that utilizes advanced sensors and machine learning algorithms to accurately identify different types of apnea in premature infants. By improving the detection and classification of AOP, healthcare providers can enhance patient care and safety. The research will be conducted in collaboration with the Children’s Hospital of Orange County, ensuring a clinical perspective in the development process.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment of apnea in premature infants, potentially reducing complications and enhancing long-term health outcomes.
How similar studies have gone: Previous research has shown promise in using advanced monitoring technologies for similar conditions, indicating potential for success in this novel approach.
Where this research is happening
-
Makani Science, INC.
Irvine, United States Active
Researchers
- Principal investigator: Chu, Michael — Makani Science, INC.
- Study coordinator: Chu, Michael
Related research
Other NIH-funded projects on the same topics.
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Continuous monitor to better detect and classify apnea in premature newborns
A small multimodal breathing monitor plus smart software designed to automatically tell what kind of apnea premature babies are having.
-
A new incubator pad to help premature infants with breathing problems.
This study is testing a new kind of pad that gently vibrates to help premature babies who have trouble breathing, with the hope of making them feel better and reducing their breathing problems.
-
Butyrate-based approach to prevent vision loss in premature babies with retinopathy
A study is exploring whether increasing butyrate levels can prevent vision-damaging retinopathy in premature infants by addressing gut bacteria and metabolic pathways.
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TopoROP: Multi-View Analysis to Diagnose Retinopathy of Prematurity
A new AI-based tool analyzes retinal images to help doctors diagnose Retinopathy of Prematurity in premature babies and other patients at risk.
-
Long-term endotypes of prematurity-related lung disease in former preemies
A long-term study looking at why some babies born very early develop lasting breathing problems and how their genes might explain these different paths.
-
Deep learning tool to diagnose retinopathy of prematurity in newborns
A new AI-based diagnostic tool uses eye images from premature babies to help clinicians identify treatment-needed retinopathy of prematurity.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.