Condition

Aortic Valve Insufficiency clinical trials and research

• 8Clinical trials
• 6Countries

Newest Aortic Valve Insufficiency clinical trials

All recruiting trials (8)

• J-VALVE versus surgical aortic valve replacement for severe aortic regurgitation

  This study will test whether the J‑VALVE transfemoral valve works as well and is as safe as surgical aortic valve replacement in people aged 65 and older with severe native aortic regurgitation.

  Recruiting at 2 sites Second Affiliated Hospital, Zhejiang University, School of Medicine · Hefei, Anhui and 27 other locations · NCT07453407

• Korea VHD Echo Study: Real-World Practice of Aortic, Mitral, and Tricuspid Valves

  This study looks at how valvular heart disease is managed in Korea by reviewing echocardiograms and medical records from multiple centers to see patterns in disease progression and treatment.

  Recruiting at 2 sites Yonsei University · Seoul, Seoul and 1 other locations · NCT07068633

• Surgery versus Trilogy transcatheter valve for treating aortic regurgitation

  This trial tests whether the Trilogy transcatheter heart valve works as well as surgical aortic valve replacement for people with significant native aortic regurgitation.

  Recruiting at 40 sites JenaValve Technology, Inc. · Burlingame, California and 39 other locations · NCT06608823

• Investigating multiple and mixed heart valve diseases

  This study looks at how common different types of heart valve diseases are and their features by gathering information from patients around the world who have been diagnosed with these conditions.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris, Île-de-France Region · NCT06235385

• Evaluating the SAPIEN X4 Heart Valve for Patients with Failing Aortic Bioprosthetic Valves

  This study is testing a new heart valve to see if it can help people with failing aortic bioprosthetic valves feel better and stay healthy.

  Recruiting at 30 sites Edwards Lifesciences · Newport Beach, California and 36 other locations · NCT05172973

• Aortic valve reconstruction in children with heart disease

  This study looks at different surgical options for fixing aortic valve problems in children with heart disease to see which methods work best and have the fewest complications.

  Recruiting National Medical Research Center for Children's Health, Russian Federation · Moscow · NCT04162444

• Registry evaluating long-term outcomes of Transcatheter aortic valve replacement

  This study looks at how well Transcatheter Aortic Valve Replacement (TAVR) works for patients over time in real-life situations.

  Recruiting at 5 sites Asan Medical Center · Stanford, California and 6 other locations · NCT03826264

• Improving TAVI outcomes with point-of-care testing for Von Willebrand Factor

  This study is testing whether quick testing for Von Willebrand Factor during TAVI procedures can help improve outcomes and reduce complications for patients with aortic stenosis.

  Recruiting at 4 sites University Hospital, Lille · Clermont-Ferrand and 8 other locations · NCT03728049

Related topics

Quick answers

How many Aortic Valve Insufficiency clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (3 trials), France (2 trials), China (2 trials), South Korea (2 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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