Condition

Prostate Cancer Metastatic clinical trials and research

• 26Clinical trials
• 43Countries

Newest Prostate Cancer Metastatic clinical trials

All recruiting trials (26)

• Epidemiology, diagnosis, and treatment patterns of prostate cancer in Algeria

  This project collects medical and treatment information to see how prostate cancer is diagnosed and managed in Algerian men with confirmed disease.

  Recruiting at 21 sites Société Algérienne de Formation et Recherche en Oncologie · Adrar, Algeria and 23 other locations · NCT07484971

• OM-RCA-01 (anti-FGFR1 antibody) for metastatic tumors that express FGFR1

  This trial will try OM-RCA-01, an IV antibody given every two weeks, in adults with metastatic cancers whose tumors test positive for FGFR1 and who have progressed after standard treatments.

  Recruiting at 4 sites Phase 1/2 Kidney Cancer Research Bureau · Kazan' and 4 other locations · NCT07292168

• First-in-human testing of repeated autologous TIL immunotherapy for metastatic colorectal and prostate cancer

  This trial tests whether repeated infusions of a patient’s own tumor-infiltrating lymphocytes (TILs) can persist longer in the blood and help people with metastatic colorectal or prostate cancer.

  Recruiting Phase 1/2 CuraCell TX AB · Frankfurt · NCT07255664

• PSMA PET to predict treatment response in advanced prostate cancer

  This will test whether PSMA PET scans can help predict how advanced prostate cancer will respond to systemic treatments such as hormone therapy, chemotherapy, or PSMA-targeted radioligand therapy.

  Recruiting at 4 sites IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, Italy and 3 other locations · NCT07089550

• Treatment for advanced prostate cancer using Pluvicto

  This study is testing if a new treatment called Pluvicto can help men with advanced prostate cancer that has spread to their bones feel better and improve their quality of life.

  Recruiting Phase 2 Excel Diagnostics and Nuclear Oncology Center · Houston, Texas · NCT06972628

• 7-day water-only fasting for metastatic prostate cancer

  This study will test whether a 7-day water-only fast (with a ketogenic very low-calorie option) is safe and doable for people with metastatic prostate cancer.

  Recruiting Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Baltimore, Maryland · NCT06826924

• Treatment for HER2-Positive Metastatic Castration-Resistant Prostate Cancer

  This study is testing a new drug called Enhertu to see if it can help people with a specific type of advanced prostate cancer who haven't had success with other treatments.

  Recruiting Phase 2 Washington D.C. Veterans Affairs Medical Center · Washington D.C., District of Columbia · NCT06610825

• Evaluating 177Lu-PSMA-617 in men with poor response to prostate cancer treatment

  This study is testing if adding a new treatment called 177Lu-PSMA-617 to standard care can help men with prostate cancer who aren’t responding well to their current treatment.

  Recruiting at 3 sites Phase 3 Unicancer · Angers and 24 other locations · NCT06496581

• Dynamic 68Ga-PSMA and 18F-FDG PET/CT scans before 177Lu-PSMA treatment

  This will test whether dynamic 68Ga‑PSMA and 18F‑FDG PET/CT scans can better identify men with metastatic castration‑resistant prostate cancer who are likely to benefit from 177Lu‑PSMA therapy.

  Recruiting Centre Henri Becquerel · Rouen · NCT06450548

• Testing new treatments for metastatic hormone-sensitive prostate cancer

  This study is testing if new treatments for metastatic hormone-sensitive prostate cancer can help patients live longer and slow down the cancer compared to standard care.

  Recruiting at 18 sites Phase 3 University College, London · Barnsley and 17 other locations · NCT06320067

• Collecting data on prostate cancer patients treated with Lu-PSMA therapy

  This study is trying to learn more about how well Lu-PSMA therapy works for men with advanced prostate cancer by collecting data and blood samples from patients receiving the treatment.

  Recruiting Erasmus Medical Center · Rotterdam, South Holland · NCT06260410

• Using a new type of PET scanner for imaging prostate cancer and related conditions

  This study is testing a new type of PET scanner to see if it can better detect early signs of prostate cancer and related conditions in patients.

  Recruiting Jagiellonian University · Krakow · NCT06242119

• Evaluating frailty and side effects in older men with metastatic prostate cancer receiving hormone therapy

  This study is trying to find out what makes older men with advanced prostate cancer feel weaker and have side effects while they are on hormone therapy.

  Recruiting University of Chicago · Chicago, Illinois · NCT06215508

• Counseling tool for Black men with metastatic prostate cancer

  This study tests a new counseling tool to see if it helps Black men with metastatic prostate cancer understand genetic testing better and if they find it useful.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06171139

• Personalized exercise program for men with metastatic prostate cancer

  This study will try a 12-week personalized aerobic and resistance exercise program to see if it lowers circulating tumor cells in men with advanced prostate cancer.

  Recruiting Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Baltimore, Maryland · NCT06165302

• Using blood tests to predict treatment response in advanced prostate cancer

  This study is testing if blood tests can help predict how well men with advanced prostate cancer will respond to their treatment.

  Recruiting at 3 sites Duke University · New York, New York and 2 other locations · NCT06141993

• Comparing Opevesostat to Other Treatments for Advanced Prostate Cancer

  This study is testing if a new drug called opevesostat can help people with advanced prostate cancer live longer and have fewer problems with their disease compared to other treatments they’ve already tried.

  Recruiting at 235 sites Phase 3 Merck Sharp & Dohme LLC · Orange, California and 287 other locations · NCT06136624

• Using targeted radiotherapy to improve outcomes in men with metastatic prostate cancer

  This study is testing if a special type of targeted radiotherapy can help men with advanced prostate cancer who have responded well to standard treatments stay healthy longer.

  Recruiting Phase 2 Centre hospitalier de l'Université de Montréal (CHUM) · Montreal, Quebec · NCT05457699

• Treatment for recurrent prostate cancer with metastases

  This study is testing whether combining hormone therapy with targeted radiation or surgery can help men with recurrent prostate cancer live longer without their cancer spreading.

  Recruiting Phase 3 Universitaire Ziekenhuizen KU Leuven · Leuven · NCT05352178

• Exercise program to improve heart health in Black men with prostate cancer on hormone therapy

  This study is testing whether a special exercise program can help improve heart health and overall well-being in Black men with prostate cancer who are receiving hormone therapy.

  Recruiting Dana-Farber Cancer Institute · Boston, Massachusetts · NCT05327465

• Using FTT PET/CT scans to evaluate PARP activity in metastatic prostate cancer

  This study is testing if a new type of scan can help see how active a certain protein is in men with metastatic prostate cancer before and after they start a new treatment.

  Recruiting Early Phase 1 Abramson Cancer Center at Penn Medicine · Philadelphia, Pennsylvania · NCT05242744

• Using PSMA-PET/CT to guide lymph node surgery in prostate cancer patients

  This study is testing if using a special imaging technique called PSMA-PET/CT can help doctors decide if prostate cancer patients need extra lymph node surgery to avoid unnecessary procedures and complications.

  Recruiting Canisius-Wilhelmina Hospital · Nijmegen, Gelderland · NCT05000827

• Stereotactic body radiotherapy for hormone-sensitive prostate cancer with few metastases

  This study is testing whether a special type of targeted radiation therapy combined with standard treatment can help men with hormone-sensitive prostate cancer that has spread to a few places live longer and feel better.

  Recruiting at 7 sites Umeå University · Lund, Lund and 6 other locations · NCT04983095

• Evaluating ADT with or without darolutamide for prostate cancer patients with vulnerable functional ability

  This study is testing if adding darolutamide to standard hormone therapy can help men with advanced prostate cancer who have some health challenges feel better and live longer.

  Recruiting at 87 sites Phase 3 Unicancer · Charleroi and 94 other locations · NCT04916613

• Combining surgery and targeted radiotherapy for advanced prostate cancer

  This study is testing whether combining surgery with targeted radiotherapy can help men with advanced prostate cancer that has spread to a few bones.

  Recruiting Phase 1/2 Herlev Hospital · Herlev · NCT04086290

• Evaluating how race and ethnicity affect treatment response in prostate cancer

  This study is testing how well standard prostate cancer treatments work for men of different races and ethnicities, especially African American men, to see if these factors affect their treatment outcomes.

  Recruiting at 2 sites Phase 2 Baylor College of Medicine · Houston, Texas and 2 other locations · NCT03833921

Related topics

Quick answers

How many Prostate Cancer Metastatic clinical trials are recruiting right now?

26, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 43 countries. The most sites are in United States (10 trials), Netherlands (4 trials), France (4 trials), Italy (3 trials), Sweden (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 5, Phase 2: 4, Phase 1/2: 3, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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