Identifying biomarkers to improve prostate cancer treatment outcomes after surgery.
Official title: Molecular Biomarkers of Long-Term Response to Androgen Deprivation Therapy and Radiation in Prostate Cancer
Funded at Washington University · NIH-11003668 · Data updated 2026-11-12
This study is looking at how certain biological markers can help doctors figure out which men with prostate cancer, who have had surgery, will respond best to hormone therapy and radiation, so they can personalize treatments for better results.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | January 1, 2022 |
| Project end | December 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $633,122 |
| NIH project number | 5R01CA260066-04 |
| Project ID | NIH-11003668 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men diagnosed with localized prostate cancer who have undergone radical prostatectomy and are at risk of recurrence.
✕Less likely to help
Patients with advanced prostate cancer or those who have not undergone surgery may not benefit from this research.
What this research studies
This research investigates how molecular biomarkers can predict long-term responses to androgen deprivation therapy and radiation in men with prostate cancer who have undergone surgery. By analyzing data from previous clinical trials, the study aims to determine which patients are most likely to benefit from additional treatments and how to tailor these treatments for better outcomes. The approach involves examining patient samples and clinical data to identify patterns that could guide future treatment decisions.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment strategies for prostate cancer patients, potentially reducing recurrence rates.
How similar studies have gone: Previous studies have shown promise in using biomarkers to guide prostate cancer treatment, indicating that this approach could be beneficial.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Maher, Christopher a — Washington University
- Study coordinator: Maher, Christopher a
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.