Condition

Prostate Cancer Metastatic Disease clinical trials and research

• 10Clinical trials
• 4Countries

Newest Prostate Cancer Metastatic Disease clinical trials

All recruiting trials (10)

• PSMA-targeted fluorescent dye OTL78 to guide prostate cancer surgery

  This study tests whether the PSMA-targeted fluorescent dye OTL78, used with near-infrared imaging, can help doctors better find and remove prostate cancer tissue during surgery in men with confirmed prostate cancer.

  Recruiting at 2 sites Phase 2/3 Indiana University · Carmel, Indiana and 1 other locations · NCT07725523

• Using PSMA PET with MRI to watch for prostate cancer returning after focal therapy

  We will try adding a PSMA PET scan to routine MRI follow-up to see if it finds prostate cancer coming back sooner in men who had focal (partial gland) therapy.

  Recruiting University of Chicago · Chicago, Illinois · NCT07115914

• Mini-tumors to guide treatment for aggressive prostate cancer

  We will grow tiny, patient-derived mini-tumors in the lab to test which treatments work best for men with aggressive or metastatic prostate cancer.

  Recruiting Maastricht Radiation Oncology · Heerlen, Limburg and 2 other locations · NCT07004582

• Combining radiotherapy or surgery with intense hormone therapy for advanced prostate cancer

  This study is testing if combining surgery or radiation with strong hormone therapy can help men with newly diagnosed advanced prostate cancer feel better and live longer.

  Recruiting Phase 2 The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Nanjing, Jiangsu · NCT06992232

• SRT for bone and lymph node metastases in advanced prostate cancer

  This trial tests whether treating multiple metastatic lesions with stereotactic radiotherapy can prolong pain control and prevent complications in men with advanced, treatment‑refractory prostate cancer.

  Recruiting Institut Cancerologie de l'Ouest · Saint-Herblain · NCT06978296

• Fezolinetant to reduce hot flashes in men on androgen-deprivation therapy

  This trial will test whether taking fezolinetant once daily for 4 weeks reduces how often and how severe hot flashes are in men with prostate cancer who are on androgen-deprivation therapy.

  Recruiting Phase 2 Brigham and Women's Hospital · Boston, Massachusetts · NCT06957691

• New hormone therapy plus PSMA PET/CT–guided local treatment for metastatic hormone‑sensitive prostate cancer

  This trial will test whether adding local treatments guided by PSMA PET/CT to standard hormone therapy helps men with newly diagnosed metastatic hormone‑sensitive prostate cancer.

  Recruiting Phase 2 Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06832774

• Evaluating imaging response biomarkers in advanced prostate cancer treatment

  This study is testing a new imaging method to see if a specific treatment for advanced prostate cancer can help doctors spot tumor growth early and adjust treatment when needed.

  Recruiting University Hospital, Grenoble · Grenoble · NCT06828263

• Investigating the impact of diet on African American and white men with prostate cancer on hormone therapy

  This study is testing if a special diet can help African American and white men with prostate cancer on hormone therapy lose weight and improve heart health.

  Recruiting at 2 sites University of California, Los Angeles · Los Angeles, California and 1 other locations · NCT06682390

• Evaluating prostate cancer using FAPI PET/MRI scans

  This study is testing if a special type of scan can help doctors better diagnose and monitor prostate cancer in patients who already have the disease.

  Recruiting Phase 2 University of Wisconsin, Madison · Madison, Wisconsin · NCT06675357

Related topics

Quick answers

How many Prostate Cancer Metastatic Disease clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (5 trials), France (2 trials), China (2 trials), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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