How hormone therapy affects blood pressure and kidney function in men
Official title: Neural and Renal Contributions to Hypertension with Androgen Deprivation Therapy
Funded at University of Colorado Denver · NIH-10897020 · Data updated 2026-11-12
This study is looking at how hormone therapy for prostate cancer affects blood pressure and kidney health in men, aiming to find ways to help manage blood pressure better during treatment.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | August 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $166,201 |
| NIH project number | 5K01HL164978-02 |
| Project ID | NIH-10897020 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men diagnosed with prostate cancer who are starting androgen deprivation therapy.
✕Less likely to help
Patients who are not undergoing androgen deprivation therapy or those with conditions unrelated to prostate cancer may not benefit from this research.
What this research studies
This research investigates how androgen deprivation therapy (ADT) influences blood pressure and kidney function in men, particularly those undergoing treatment for prostate cancer. The study focuses on understanding the relationship between testosterone levels, inflammation, and the body's ability to regulate blood pressure. By assessing neural and renal contributions to hypertension, the research aims to identify mechanisms that may lead to better management of blood pressure in patients receiving ADT. Participants will be men diagnosed with prostate cancer who are undergoing this specific therapy.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing hypertension in men undergoing hormone therapy.
How similar studies have gone: Previous research has indicated that hormonal changes can significantly impact blood pressure regulation, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Babcock, Matthew C — University of Colorado Denver
- Study coordinator: Babcock, Matthew C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.