Condition

Alzheimer Disease, Early Onset clinical trials and research

• 14Clinical trials
• 7Countries

Newest Alzheimer Disease, Early Onset clinical trials

All recruiting trials (14)

• DNL628 safety, tolerability, and drug behavior in people with early Alzheimer's disease.

  This trial will test DNL628 versus placebo in people with early Alzheimer's disease to see if it is safe, well tolerated, and how the body handles the drug.

  Recruiting at 4 sites Phase 1 Denali Therapeutics Inc. · 's-Hertogenbosch and 3 other locations · NCT07328451

• Targeted magnetic stimulation of the precuneus to slow cognitive decline in Alzheimer's

  This will try repetitive magnetic brain stimulation of the precuneus to see if it slows memory and thinking decline in people aged 50–85 with biomarker-confirmed mild Alzheimer's.

  Recruiting Amsterdam UMC, location VUmc · Amsterdam · NCT07036328

• Exploring how music affects people with Alzheimer's and Parkinson's diseases

  This study looks at how music affects people over 60 with Alzheimer's and Parkinson's diseases compared to healthy older adults to see how it influences their emotions and enjoyment of music.

  Recruiting University Hospital, Montpellier · Montpellier, Hérault and 2 other locations · NCT06688968

• Improving symptoms of mild cognitive impairment and early dementia with brain stimulation

  This study is testing a new brain stimulation treatment combined with mental exercises to see if it can help people with mild cognitive impairment and early dementia feel better.

  Recruiting University of Campania Luigi Vanvitelli · Caserta, Italy · NCT06668610

• Biobank for studying ALS and Alzheimer's diseases

  This study is collecting blood, skin samples, and health information from people to see how genetics might help us understand and find treatments for ALS and Alzheimer's disease.

  Recruiting New York Stem Cell Foundation Research Institute · New York, New York · NCT06203106

• Exploring brain microstructure in early Alzheimer's disease

  This study is trying to see if special brain scans can help identify early signs of Alzheimer's disease in people with mild cognitive issues and those who feel their memory is slipping.

  Recruiting Rennes University Hospital · Rennes · NCT06099587

• Discovering biomarkers for early diagnosis of Alzheimer's and Parkinson's diseases

  This study is testing if simple and affordable brain scans can help find early signs of Alzheimer's and Parkinson's diseases in people with mild cognitive issues or newly diagnosed Parkinson's.

  Recruiting Rennes University Hospital · Rennes · NCT06080659

• Using light and sound therapy to treat Alzheimer's disease

  This study is testing whether a light and sound device can help people with mild Alzheimer's disease improve their memory and brain function over six months.

  Recruiting Massachusetts Institute of Technology · Cambridge, Massachusetts · NCT05655195

• Lifestyle interventions for early onset Alzheimer's disease

  This study is testing if a mix of brain training on a computer and Tai Chi-Qi Gong exercises can help people with early-onset Alzheimer's feel better and improve their thinking and mood.

  Recruiting Indiana University · Indianapolis, Indiana · NCT05573490

• Cohort study on Dampness Syndrome in Traditional Chinese Medicine

  This study is looking at how Dampness Syndrome in Traditional Chinese Medicine might be linked to chronic diseases like diabetes, cancer, and dementia in people aged 35 to 75 over five years.

  Recruiting Guangzhou University of Traditional Chinese Medicine · Guangzhou, Guangdong · NCT05315895

• Comparing Donepezil and non-drug treatments for Alzheimer's disease

  This study is testing whether adding the medication Donepezil to standard non-drug care can help people with Alzheimer's disease feel better after six months.

  Recruiting Phase 3 Assistance Publique - Hôpitaux de Paris · Paris · NCT04661280

• GnRH therapy to improve cognition in individuals with Down syndrome

  This study is testing if a new hormone treatment can help improve thinking skills and smell in adults with Down syndrome who are at risk for early Alzheimer's disease.

  Recruiting Phase 2/3 Centre Hospitalier Universitaire Vaudois · Lausanne, Canton of Vaud · NCT04390646

• Understanding brain resilience in Alzheimer's disease and its variants

  This study is trying to understand how some people with Alzheimer's disease, especially those with early symptoms, can stay resilient and cope better by looking at their brain scans and thinking abilities.

  Recruiting at 2 sites Institut National de la Santé Et de la Recherche Médicale, France · Orsay and 1 other locations · NCT04150198

• Longitudinal imaging study of Alzheimer's disease

  This study is testing how the buildup of certain proteins in the brains of people with different types of Alzheimer's disease changes over a year to better understand the disease's progression.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT02740634

Related topics

Quick answers

How many Alzheimer Disease, Early Onset clinical trials are recruiting right now?

14, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in France (5 trials), United States (4 trials), Netherlands (2 trials), Italy (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1, Phase 3: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →