Exploring how music affects people with Alzheimer's and Parkinson's diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter observational pilot study aims to compare musical engagement behaviors in individuals aged over 60 with Alzheimer's disease, Parkinson's disease, and healthy elderly controls. Participants will undergo a two-hour interview with a neuropsychologist, which includes demographic data collection and neuropsychological assessments. The study seeks to understand how different cognitive dysfunctions impact emotional engagement and sensitivity to musical rewards, thereby creating distinct profiles for each condition. By investigating these aspects, the study hopes to shed light on the therapeutic potential of music in neurodegenerative diseases.

Why it matters

Who can join: the full rules

Inclusion Criteria:

General inclusion criteria:

* 60 years and older
* French-speaking and volunteering for the study
* Living at home with a relative

Alzheimer's disease inclusion criteria:

* Biological diagnosis of probable Alzheimer's disease according to NINCDS-ADRDA criteria (McKhann et al., 1984)
* MMSE greater than or equal to 20

Inclusion criteria Parkinson's disease :

* Diagnosis of Idiopathic Parkinson's disease
* MMSE greater than or equal to 20

Exclusion Criteria:

* No known neurological pathologies (epilepsy and other non-degenerative CNS diseases) or psychiatric disorders (chronic psychosis and psychotic episodes)
* Autistic disorders
* History of stroke or head trauma
* Unstable medical condition (cancer)
* Subject unable to read and/or write
* Hearing impairment without hearing aids
* Refusal of consent after information
* Persons unable to give consent, research carried out in emergency situations, etc.)
* Non-affiliation with a social security scheme
* Person deprived of liberty (by judicial or administrative decision, or forced hospitalization)
* Person under legal protection (guardianship, curatorship, legal protection)
* Person participating in another research project with an exclusion period still in progress

Where it's running

• CHU de Montpellier - CEPMo
  Montpellier, Hérault, France Recruiting
• Montpellier Seniors' Association
  Montpellier, Hérault, France Not yet recruiting
• CHU de Montpellier - CMRR
  Montpellier, Hérault, France Not yet recruiting

Study contacts

• Principal investigator: Karim Bennys, Md — University Hospital, Montpellier
• Study coordinator: Mikaël Genguelou, PhD
• Email: mikael.genguelou@univ-montp3.fr
• Phone: 06.04.45.37.94.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.