Using Tranexamic Acid to Reduce Bleeding During Wisdom Tooth Removal
Investigation of the Effects of Tranexamic Acid Solution Irrigation on Bleeding, Surgical Field Visibility, and Postoperative Edema in the Extraction of Horizontally Impacted Third Molars
This study is testing if using tranexamic acid during wisdom tooth removal can help reduce bleeding and swelling for healthy patients who need their impacted teeth taken out.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 20 (estimated) |
| Ages | 14 Years to 40 Years |
| Sex | All |
| Sponsor | Bezmialem Vakif University Academic / other |
| Locations | 1 site (Istanbul, Fatih) |
| Trial ID | NCT06806241 on ClinicalTrials.gov |
What this trial studies
This study investigates the use of tranexamic acid (TXA) irrigation during the surgical extraction of impacted third molars to assess its effectiveness in reducing intraoperative blood loss and postoperative edema. TXA is a hemostatic agent that can be applied topically to minimize systemic absorption and potential side effects. The study will involve patients who are systemically healthy and require the extraction of bilaterally impacted third molars with bone retention. By comparing outcomes with and without TXA irrigation, the study aims to provide insights into its safety and efficacy in dental surgery.
Who should consider this trial
Good fit: Ideal candidates are systemically healthy individuals aged 14-40 years who require the extraction of bilaterally impacted third molars.
Not a fit: Patients with systemic diseases, bleeding disorders, or advanced infections associated with the impacted tooth may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce bleeding and improve recovery outcomes for patients undergoing wisdom tooth extraction.
How similar studies have performed: Previous studies have shown success with TXA in other surgical contexts, but its application in dental extractions is novel and untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Indicated for the Extraction of Bilaterally Impacted Third Molars with Bone Retention. 2. Systemically healthy patients aged 14-40 years with no bleeding disorders. Exclusion Criteria: 1. Patients with systemic diseases affecting general health. 2. Patients diagnosed with any bleeding disorder. 3. Patients with advanced infection or cysts associated with the impacted tooth.
Where this trial is running
Istanbul, Fatih
- Bezmialem Vakıf Universty — Istanbul, Fatih, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Taha Pergel, Asist.Prof
- Email: tahapergel_05@hotmail.com
- Phone: +902124531850
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.