Beta-Tricalcium Phosphate for preserving the ridge after tooth extraction
Official title: Assessment of Safety and Performance of Neobone®: A Prospective Observational Study in the Field of Dentistry
Run by Egas Moniz - Cooperativa de Ensino Superior, CRL · NCT07638319 · Data updated 2026-11-12
This early-phase trial tests whether beta-tricalcium phosphate helps preserve bone volume after tooth extraction compared with natural healing.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Egas Moniz - Cooperativa de Ensino Superior, CRL Academic / other |
| Locations | 1 site (Caparica, Monte Da Caparica) |
| Status | Recruiting |
| Started | December 1, 2025 |
| Main results expected | December 2026 |
| Study ends | December 2028 |
| Registry record updated | June 11, 2026 |
| Trial ID | NCT07638319 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older needing extraction with type 1 or 2 sockets, who can consent and meet health criteria.
✕Probably not a fit
Patients with active infection, uncontrolled diabetes or periodontal disease, heavy smoking, or other contraindications may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this randomized, early-phase study, participants needing a tooth extraction are assigned to receive beta-tricalcium phosphate graft material or allow natural healing. Procedures include CBCT and intra-oral scans after extraction and at six months to measure bone height, width, and density at the extraction site. The goal is to determine if the grafted sockets better maintain ridge volume for future implant placement. Eligible adults provide informed consent and must meet criteria related to socket type and health status. Safety and feasibility are monitored through standard exclusion criteria to minimize infection risk and ensure suitability for implant-related procedures.
Why it matters
Potential benefit: If successful, beta-tricalcium phosphate could improve ridge preservation, potentially facilitating later implant placement.
How similar studies have gone: Prior studies in similar bone graft materials have shown variable but promising results for ridge preservation, making this approach worth testing.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years or older * Acceptance of informed consent * Type 1 or 2 extraction sockets (Elian et al. 2007) Exclusion Criteria: * Presence of active infection or severe inflammation in the intervention zone * Relevant medical history that contraindicates implant surgery * Patients with poor oral hygiene (full-mouth plaque score and full-mouth bleeding score \>15%) and lack of motivation * Uncontrolled diabetes (reported levels of glycated haemoglobin exceeding 7%) * Uncontrolled and /or untreated periodontal disease * Heavy smokers (more than 10 cigarettes per day) * Immunosuppression
Where it's running
-
Clinica Dentária Egas Moniz
Caparica, Monte Da Caparica, Portugal Recruiting
Study contacts
- Study coordinator: Angel Lobito, Masters' in Dentistry
- Email: alobito@egasmoniz.edu.pt
- Phone: 00351924347050
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Effect of four post-extraction socket approaches on preserving the ridge after tooth removal
This study tests four ways to care for an extraction socket to see which best preserves the jawbone and gum after tooth removal for future implants.
-
Ridge Preservation With Collagen Membrane After Tooth Extraction
This study tests whether adding a resorbable collagen membrane to a bone graft improves jawbone preservation after tooth extraction for people who have significant buccal bone loss.
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Reduced wait time for implant placement after socket preservation with Vega Plus implants
This will test whether placing a single-tooth Vega Plus implant four months after extraction and ridge preservation works as well or better than waiting six months for adults who need a single-tooth implant.
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We will see if a socket that widens right after a tooth is removed or stays the same changes ridge width and height four months later in adults having a single extraction with bone graft and a resorbable membrane.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.