Clinical trial Recruiting at 1 site Early Phase 1 Interventional Ages 18 and up

Beta-Tricalcium Phosphate for preserving the ridge after tooth extraction

Official title: Assessment of Safety and Performance of Neobone®: A Prospective Observational Study in the Field of Dentistry

Run by Egas Moniz - Cooperativa de Ensino Superior, CRL · NCT07638319 · Data updated 2026-11-12

This early-phase trial tests whether beta-tricalcium phosphate helps preserve bone volume after tooth extraction compared with natural healing.

Quick facts

PhaseEarly Phase 1
Study typeInterventional
Ages18 Years and up
SexAll
Enrollment30 (estimated)
SponsorEgas Moniz - Cooperativa de Ensino Superior, CRL
Academic / other
Locations1 site (Caparica, Monte Da Caparica)
StatusRecruiting
StartedDecember 1, 2025
Main results expectedDecember 2026
Study endsDecember 2028
Registry record updatedJune 11, 2026
Trial IDNCT07638319 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 years or older needing extraction with type 1 or 2 sockets, who can consent and meet health criteria.

Probably not a fit

Patients with active infection, uncontrolled diabetes or periodontal disease, heavy smoking, or other contraindications may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized, early-phase study, participants needing a tooth extraction are assigned to receive beta-tricalcium phosphate graft material or allow natural healing. Procedures include CBCT and intra-oral scans after extraction and at six months to measure bone height, width, and density at the extraction site. The goal is to determine if the grafted sockets better maintain ridge volume for future implant placement. Eligible adults provide informed consent and must meet criteria related to socket type and health status. Safety and feasibility are monitored through standard exclusion criteria to minimize infection risk and ensure suitability for implant-related procedures.

Why it matters

Potential benefit: If successful, beta-tricalcium phosphate could improve ridge preservation, potentially facilitating later implant placement.

How similar studies have gone: Prior studies in similar bone graft materials have shown variable but promising results for ridge preservation, making this approach worth testing.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years or older
* Acceptance of informed consent
* Type 1 or 2 extraction sockets (Elian et al. 2007)

Exclusion Criteria:

* Presence of active infection or severe inflammation in the intervention zone
* Relevant medical history that contraindicates implant surgery
* Patients with poor oral hygiene (full-mouth plaque score and full-mouth bleeding score \>15%) and lack of motivation
* Uncontrolled diabetes (reported levels of glycated haemoglobin exceeding 7%)
* Uncontrolled and /or untreated periodontal disease
* Heavy smokers (more than 10 cigarettes per day)
* Immunosuppression

Where it's running

  • Clinica Dentária Egas Moniz
    Caparica, Monte Da Caparica, Portugal
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.