Investigating fluid responsiveness and venous congestion in critically ill patients during volume expansion

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines the relationship between fluid responsiveness and venous congestion in critically ill patients undergoing a standardized fluid challenge. It aims to understand how these two factors evolve over time following fluid administration, which is crucial for guiding fluid therapy in the ICU. By utilizing hemodynamic monitoring and pulse wave contour analysis, the study seeks to provide insights into the dynamics of fluid management in critically ill patients. The findings could enhance clinical decision-making regarding fluid therapy and improve patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years
* Hospitalized in the intensive care unit (ICU)
* Hemodynamic monitoring in place, with a pulse wave contour analysis- derived estimation of cardiac output (either calibrated or uncalibrated)
* Decision made by clinicians to perform volume expansion through intravenous infusion of crystalloid fluid

Exclusion Criteria:

* Pregnancy
* Refusal to participate by relatives of the patient or the patient himself

Where it's running

• First affiliated Hospital , Sun Yat-sen University
  Guangzhou, Guangdong, China Recruiting
• Longgang Central Hospital of Shenzhen
  Shenzhen, Guangdong, China Recruiting
• Bicetre Hospital
  Paris, Val-de-Marne, France Recruiting

Study contacts

• Study coordinator: Xiang SI, MD
• Email: sixiang@mail.sysu.edu.cn
• Phone: 0626824692

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.