Hemodynamic Changes and Trigeminocardiac Reflex During Bimaxillary Orthognathic Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational cohort study conducted at Kırıkkale University to document intraoperative hemodynamic changes during bimaxillary orthognathic surgery using routine monitoring data. Researchers will record heart rate, systolic and diastolic blood pressure, mean arterial pressure, and oxygen saturation at 5-minute intervals across defined surgical stages. The occurrence of the trigeminocardiac reflex will be noted and categorized by severity, and its relationship to patient characteristics and surgical stage will be explored without any additional interventions beyond standard care. The goal is to understand patterns of autonomic responses during surgery to aid early recognition and management of intraoperative hemodynamic changes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18-40 years.
* Patients with an indication for bimaxillary orthognathic surgery.
* Patients with complete routine intraoperative hemodynamic monitoring data.
* Patients who provide written informed consent to participate in the study.

Exclusion Criteria:

* Patients without an indication for bimaxillary orthognathic surgery.
* Individuals younger than 18 years or older than 40 years.
* Patients with known cardiovascular disease, including arrhythmia, heart failure, coronary artery disease, or other significant cardiovascular disorders.
* Patients with systemic diseases, including diabetes mellitus, hypertension, thyroid disorders, or other significant systemic conditions.
* Patients with diagnosed psychiatric disorders.
* Patients with incomplete or irregularly recorded intraoperative hemodynamic monitoring data.
* Individuals who refuse to participate or do not provide written informed consent.

Where it's running

• Kırıkkale Univesity Faculty of Dentistry
  Kirikkale, Kırıkkale, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Elif Çoban, DDS — Kırıkkale University Faculty of Dentistry
• Study coordinator: Elif Assistant Professor, DDS
• Email: elifcoban@kku.edu.tr
• Phone: +90 318 224 4927

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.