Using a suprasternal ultrasound to see if heart filling changes help guide fluids in kids undergoing surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines if variation in the aortic time-velocity integral (VTI), measured through a suprasternal Doppler window, can indicate preload dependence in children under anesthesia. By comparing VTI changes to fluid responsiveness, researchers aim to identify a simple, widely available method to guide fluid management. The approach leverages existing cardiac probes in the operating room and the accessible suprasternal window. Enrollment includes children under 18 undergoing procedures requiring general anesthesia, with several exclusions to ensure safe and interpretable measurements. The goal is to reduce fluid overload and its associated risks by better predicting who will respond to fluid administration.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient under 18 admitted to paediatric operating room for a surgical intervention, an endoscopy, an interventional radiology procedure or an imagery and needing a general anaesthesia.

Exclusion Criteria:

* Condition preventing a suprasternal ultrasound (tracheostomy, spinal immobilization, suprasternal bandage)
* Pathology disturbing respiratory variation of left ventricular stroke volume (PAH, constrictive pericarditis, pericardial effusion, right ventricular dysfunction, complex congenital heart disease, aortic coarctation, patent ductus arteriosus
* Every medical condition where Berry's rule of fasting compensation could be unsafe (anuric kidney failure, oedema, heart failure with reduce left ventricular ejection fraction, patient under vasoactive drugs
* Opposition to the participation in the study
* Pregnant women
* Patient with no security coverage
* Inability to determine baseline cardiac output

Where it's running

• chu de Lille
  Lille, France Recruiting

Study contacts

• Study coordinator: Martin DUBERNET, Dr
• Email: Martin.DUBERNET@chu-lille.fr
• Phone: +33 3 20 44 59 62

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.