Using a bioimpedance device to track fluid status in children after stem cell transplant
Official title: Using Bioimpedance Analysis to Monitor Fluid Status in Children Undergoing Stem Cell Transplantation
Run by St. Jude Children's Research Hospital · NCT07834710 · Data updated 2026-11-12
The study tests whether bedside bioimpedance measurements can reliably track body water changes in children undergoing stem cell transplantation, alongside standard fluid checks.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 6 Years to 21 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | St. Jude Children's Research Hospital Academic / other |
| Locations | 1 site (Memphis, Tennessee) |
| Status | Recruiting |
| Started | November 5, 2026 |
| Main results expected | June 2027 |
| Study ends | June 2027 |
| Registry record updated | November 9, 2026 |
| Trial ID | NCT07834710 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Candidates are children and young adults aged 6–21 undergoing allogeneic or autologous HSCT at St. Jude.
✕Probably not a fit
Patients with pacemakers or those who do not have consent from the treating physician or participant/guardian are not eligible, and all others may have limited benefit depending on individual care plans.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study explores the feasibility of using serial bedside bioimpedance analysis (BIA) to monitor total body water, extracellular water, and intracellular water in pediatric HSCT patients during hospitalization. Measurements are taken pre-transplant, every other day for the first two weeks, and weekly thereafter up to one year, alongside routine nursing assessments. The study also compares BIA data with standard fluid monitoring methods such as weights and input/output records to see if BIA can support more standardized fluid management. Data will be collected from routine care, including lab and imaging when performed as part of standard practice. Eligible participants are ages 6–21 undergoing allogeneic or autologous HSCT at St. Jude, with informed consent obtained.
Why it matters
Potential benefit: If successful, BIA could provide a more standardized, objective method to monitor fluid status in pediatric HSCT patients, potentially improving fluid management.
How similar studies have gone: Previous work in adults and other populations suggests BIA can reflect fluid status, but pediatric HSCT-specific data are limited, making this largely exploratory for this setting.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ages 6-21 years planned to undergo allogeneic or autologous HSCT for any indication with any preparative regimen. Exclusion Criteria: * Pacemaker implantation due to incompatibility with the bioimpedance device * Lack of agreement from the primary HSCT physician. * Inability or unwillingness of the research participant and/or legal guardian/representative to provide written informed consent.
Where it's running
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St. Jude Children's Research Hospital
Memphis, Tennessee, United States Recruiting
Study contacts
- Principal investigator: Saad Ghafoor, MD — St. Jude Children's Research Hospital
- Study coordinator: Ghafoor Ghafoor, MD
- Email: referralinfo@stjude.org
- Phone: 888-226-4343
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.