Understanding the effects of gestational diabetes on mothers and their children

Gestational Diabetes Mellitus and Its Consequences in Mothers and Offsprings

Observational Guangzhou Women and Children's Medical Center · NCT04529889

This study looks at how gestational diabetes affects the health of mothers and their children both during and after pregnancy to find ways to reduce health risks.

Quick facts

Study typeObservational
Enrollment7000 (estimated)
SexAll
SponsorGuangzhou Women and Children's Medical Center Academic / other
Locations1 site (Guangzhou, Guangdong)
Trial IDNCT04529889 on ClinicalTrials.gov

What this trial studies

This observational study focuses on gestational diabetes mellitus (GDM) and its short-term and long-term consequences for both mothers and their offspring. It aims to establish a cohort of pregnant women diagnosed with GDM and follow their health outcomes, including risks of obesity, type 2 diabetes, and other health issues in both mothers and children. The study will collect biological samples and monitor various health parameters over time to better understand the implications of GDM. By systematically tracking these outcomes, the research seeks to identify potential interventions to mitigate risks associated with GDM.

Who should consider this trial

Good fit: Ideal candidates for this study are pregnant women diagnosed with gestational diabetes who plan to deliver at the Guangzhou Women and Children's Medical Center.

Not a fit: Patients with pre-gestational diabetes or chronic health conditions such as hypertension or kidney disease may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved health outcomes for mothers and children affected by gestational diabetes.

How similar studies have performed: Other studies have shown significant associations between gestational diabetes and long-term health risks, indicating that this approach is supported by existing research.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Pregnant women diagnosed with gestational diabetes mellitus
2. Pregnant women intended to eventually deliver in Guangzhou Women and Children's Medical Center
3. Permanent residents or families intended to remain in Guangzhou with their child for no less than 3 years

Exclusion Criteria:

1. Women with pre-gestational diabetes mellitus
2. Women with chronic hypertension or kidney disease

Where this trial is running

Guangzhou, Guangdong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Gestational Diabetes MellitusPregnancy OutcomeNeurodevelopmentImmune DevelopmentChildhood ObesityHost and MicrobiomeHyperglycaemiaMaternal health
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.