Research on twins born in Guangzhou
Twins Born in Guangzhou Cohort Study
This study is trying to understand how genes and the environment affect diseases by looking at twins born in Guangzhou, China, from birth to age 18.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | N/A to 18 Years |
| Sex | All |
| Sponsor | Guangzhou Women and Children's Medical Center Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT03331133 on ClinicalTrials.gov |
What this trial studies
The 2-BIG is a twin birth cohort study based in Guangzhou, China, aimed at understanding how genetic and environmental factors contribute to diseases. It collects extensive data on twins from birth to 18 years, including biological samples and information on family and lifestyle exposures. By utilizing a twin cohort, the study seeks to minimize biases related to age, gender, and environment, allowing for a clearer analysis of disease etiology. The research focuses on chronic diseases and aims to establish a database for calculating the heritability of traits in the Chinese population.
Who should consider this trial
Good fit: Ideal candidates for this study are live twins born at the Guangzhou Women and Children's Medical Center who are permanent residents or families intending to stay in Guangzhou for at least three years.
Not a fit: Patients who do not meet the residency requirement or are not twins born in the specified medical center may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of disease development in twins, potentially leading to improved prevention and treatment strategies.
How similar studies have performed: While twin studies are common in various populations, this specific cohort study in China is relatively rare and aims to provide novel insights into the heritability of traits associated with chronic diseases.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Live twins delivered in Guangzhou Women and Children's Medical Center 2. Permanent residents or families intended to remain in Guangzhou with their children for no less than 3 years 3. Baseline information during pregnancy available
Where this trial is running
Guangzhou, Guangdong
- Guangzhou Women and Children's Medical Center — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Principal investigator: Xiu Qiu, PhD — Born in Guangzhou Cohort Study in Guangzhou Women and Children's Medical Center
- Study coordinator: Xiu Qiu, PhD
- Email: xiu.qiu@bigcs.org/qxiu0161@163.com
- Phone: 0086 20 38367162
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.