Investigating the health effects of IVF on mothers and their children in Guangzhou
Official title: IVF Offspring Born in Guangzhou Cohort Study
Run by Guangzhou Women and Children's Medical Center · NCT03650829 · Data updated 2026-11-12
This study is trying to see how having babies through IVF affects the health of mothers and their children over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | Any age to 18 Years |
| Sex | All |
| Enrollment | 3000 (estimated) |
| Sponsor | Guangzhou Women and Children's Medical Center Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Status | Recruiting |
| Started | February 1, 2012 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2038 |
| Registry record updated | February 26, 2024 |
| Trial ID | NCT03650829 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are pregnant women under 20 weeks of gestation who have conceived through assisted reproductive technology and plan to deliver at the Guangzhou Women and Children's Medical Center.
✕Probably not a fit
Patients who conceived naturally or those who do not intend to remain in Guangzhou for at least three years may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The IVF Offspring Born in Guangzhou Cohort Study aims to explore the short- and long-term health effects of assisted reproductive technology (ART) on mothers and their offspring. This observational study collects data on various factors including environmental, occupational, and lifestyle exposures, as well as health outcomes in later life. Biological samples such as blood and tissue are also gathered from participants to better understand the implications of ART. The study addresses concerns regarding potential health risks associated with ART, including increased cancer risks in mothers and chronic diseases in IVF offspring.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the health risks associated with ART, leading to improved care and outcomes for mothers and their children.
How similar studies have gone: Other studies have indicated potential health risks associated with ART, suggesting that this cohort study builds on existing knowledge but focuses on a specific population in Guangzhou.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pregnant women with \<20 weeks of gestation * Pregnant women intended to eventually deliver in Guangzhou Women and Children's Medical Center * Permanent residents or families intended to remain in Guangzhou with their child for ≥3 years * Pregnant women conceived by assited reproductive technology Exclusion Criteria: • None
Where it's running
-
Guangzhou Women and Children's Medical Center
Guangzhou, Guangdong, China Recruiting
Study contacts
- Principal investigator: Xiu Qiu, PhD — Guangzhou Women and Children's Medical Center, China
- Study coordinator: Xiu Qiu, PhD
- Email: qxiu0161@163.com
- Phone: 0086 20 38367160
Similar studies
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Exploring the impact of maternal grandmothers on child health in Guangzhou
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Research on twins born in Guangzhou
This study is trying to understand how genes and the environment affect diseases by looking at twins born in Guangzhou, China, from birth to age 18.
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Investigating early life exposures and their health effects in Guangzhou
This study looks at how early life experiences, like the environment and lifestyle, affect the health of mothers and their children in Guangzhou, China, especially concerning issues like high blood sugar during pregnancy and childhood obesity.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.