Investigating early life exposures and their health effects in Guangzhou
Official title: The Born in Guangzhou Cohort Study (BIGCS)
Run by Guangzhou Women and Children's Medical Center · NCT02526901 · Data updated 2026-11-12
This study looks at how early life experiences, like the environment and lifestyle, affect the health of mothers and their children in Guangzhou, China, especially concerning issues like high blood sugar during pregnancy and childhood obesity.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 30000 (estimated) |
| Sponsor | Guangzhou Women and Children's Medical Center Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Status | Recruiting |
| Started | February 1, 2012 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2030 |
| Registry record updated | February 26, 2024 |
| Trial ID | NCT02526901 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are pregnant women under 20 weeks of gestation who plan to deliver at the Guangzhou Women and Children's Medical Center.
✕Probably not a fit
Patients who are not pregnant or those who do not intend to remain in Guangzhou for at least three years may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The Born in Guangzhou Cohort Study (BIGCS) aims to explore the short- and long-term health effects of early life exposures on individuals in Guangzhou, China. This observational study collects data on environmental, occupational, and lifestyle factors, as well as health outcomes, from pregnant women and their children. Biological samples, including blood and tissue, are also gathered to support the research. The study focuses on understanding how rapid economic development and lifestyle changes impact health, particularly concerning conditions like intrauterine hyperglycemia and childhood obesity.
Why it matters
Potential benefit: If successful, this study could provide insights into preventing chronic diseases and improving health outcomes for future generations.
How similar studies have gone: Other studies have shown success in examining the effects of early life exposures on health, making this approach both relevant and valuable.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pregnant women with \<20 weeks of gestation * Pregnant women intended to eventually deliver in Guangzhou Women and Children's Medical Center * Permanent residents or families intended to remain in Guangzhou with their child for ≥3 years
Where it's running
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Guangzhou Women and Children's Medical Center
Guangzhou, Guangdong, China Recruiting
Study contacts
- Principal investigator: Xiu Qiu, PhD — Guangzhou Women and Children's Medical Center, China
- Study coordinator: Xiu Qiu, PhD
- Email: qxiu0161@163.com
- Phone: 0086 20 38367160
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Exploring the impact of maternal microbiota on child health
This study looks at how the bacteria in pregnant women's bodies affect their babies' health and development to see if it can help prevent future health issues.
-
Understanding the effects of gestational diabetes on mothers and their children
This study looks at how gestational diabetes affects the health of mothers and their children both during and after pregnancy to find ways to reduce health risks.
-
Exploring the impact of maternal grandmothers on child health in Guangzhou
This study looks at how maternal grandmothers in Guangzhou, China, might affect the health of their grandchildren by examining both genetics and lifestyle factors.
-
Research on twins born in Guangzhou
This study is trying to understand how genes and the environment affect diseases by looking at twins born in Guangzhou, China, from birth to age 18.
-
Exploring factors affecting preterm birth and its outcomes in children
This study is looking at how genetics and the environment affect preterm birth and its impact on the health of children over time.
-
Investigating the health effects of IVF on mothers and their children in Guangzhou
This study is trying to see how having babies through IVF affects the health of mothers and their children over time.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.