Investigating early life exposures and their health effects in Guangzhou
The Born in Guangzhou Cohort Study (BIGCS)
This study looks at how early life experiences, like the environment and lifestyle, affect the health of mothers and their children in Guangzhou, China, especially concerning issues like high blood sugar during pregnancy and childhood obesity.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30000 (estimated) |
| Sex | All |
| Sponsor | Guangzhou Women and Children's Medical Center Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT02526901 on ClinicalTrials.gov |
What this trial studies
The Born in Guangzhou Cohort Study (BIGCS) aims to explore the short- and long-term health effects of early life exposures on individuals in Guangzhou, China. This observational study collects data on environmental, occupational, and lifestyle factors, as well as health outcomes, from pregnant women and their children. Biological samples, including blood and tissue, are also gathered to support the research. The study focuses on understanding how rapid economic development and lifestyle changes impact health, particularly concerning conditions like intrauterine hyperglycemia and childhood obesity.
Who should consider this trial
Good fit: Ideal candidates for this study are pregnant women under 20 weeks of gestation who plan to deliver at the Guangzhou Women and Children's Medical Center.
Not a fit: Patients who are not pregnant or those who do not intend to remain in Guangzhou for at least three years may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into preventing chronic diseases and improving health outcomes for future generations.
How similar studies have performed: Other studies have shown success in examining the effects of early life exposures on health, making this approach both relevant and valuable.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pregnant women with \<20 weeks of gestation * Pregnant women intended to eventually deliver in Guangzhou Women and Children's Medical Center * Permanent residents or families intended to remain in Guangzhou with their child for ≥3 years
Where this trial is running
Guangzhou, Guangdong
- Guangzhou Women and Children's Medical Center — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Principal investigator: Xiu Qiu, PhD — Guangzhou Women and Children's Medical Center, China
- Study coordinator: Xiu Qiu, PhD
- Email: qxiu0161@163.com
- Phone: 0086 20 38367160
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.