Exploring the impact of maternal grandmothers on child health in Guangzhou
Maternal Grandmothers in the Born in Guangzhou Cohort Study
This study looks at how maternal grandmothers in Guangzhou, China, might affect the health of their grandchildren by examining both genetics and lifestyle factors.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | 36 Years to 100 Years |
| Sex | Female |
| Sponsor | Guangzhou Women and Children's Medical Center Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT03633162 on ClinicalTrials.gov |
What this trial studies
The MGBIG study investigates the cross-generational effects of maternal grandmothers on the health of their grandchildren in Guangzhou, China. It aims to understand how genetic and environmental factors influence disease development across three generations: grandmother, mother, and child. The study collects extensive data on lifestyle, environmental exposures, and health history, along with biological samples from participants. By focusing on this unique cohort, the research seeks to uncover the role of maternal grandmothers in shaping the health outcomes of future generations.
Who should consider this trial
Good fit: Ideal candidates for this study are maternal grandmothers of children born at the Guangzhou Women and Children's Medical Center.
Not a fit: Patients with significant cardiovascular abnormalities or intellectual disabilities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into how maternal grandmothers influence the health and development of their grandchildren, potentially leading to improved health strategies.
How similar studies have performed: While the concept of cross-generational health effects is gaining attention, this specific approach focusing on maternal grandmothers is relatively novel and has not been extensively tested in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Maternal Grandmother' grandchildren delivered in Guangzhou Women and Children's Medical Center 2. Baseline information of maternal grandmother's daughter during pregnancy available Exclusion Criteria: 1. Significant cardiovascular abnormalities 2. Intelligent obstacle, intellectual disabilities or gawkish condition
Where this trial is running
Guangzhou, Guangdong
- Guangzhou Women and Children's Medical Center — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Principal investigator: Xiu Qiu, PhD — Guangzhou Women and Children's Medical Center, China
- Study coordinator: Xiu Qiu, PhD
- Email: qxiu0161@163.com
- Phone: 0086 20 38367160
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.