Two EMG Monitors for Deep NMB During Robotic/Thoracic Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this prospective, intraoperative device comparison, adults undergoing elective laparoscopic/robotic or VATS surgeries with deep neuromuscular blockade will have both monitoring devices used simultaneously on opposite arms. Standard anesthesia care is provided, with rocuronium for blockade and sugammadex for reversal, and neuromuscular function is tracked via TOF, TOF ratio, and PTC at predefined time points. Outcomes include device performance, signal quality, and the ability to detect spontaneous diaphragmatic movements and breath-initiation efforts, along with usability surveys for clinicians.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult male or female patients aged ≥ 18 years old.
* Patients undergo elective abdominal laparoscopic/robotic or thoracic video-assisted (VAT) surgeries requiring general anesthesia for greater than 3 hours at The Ohio State University Wexner Medical Center.
* Able to provide a signed, written informed consent.
* Able to speak, read, and write in English.
* ASA physical status I-III.

Exclusion Criteria:

* Patients who require emergency surgery or an emergent intervention.
* Any documented cognitive or psychological disorders that, in the investigator's opinion, can interfere with the patient's pain perception.
* Vulnerable populations: pregnant females, prisoners, breastfeeding.
* Presence of any medical condition that, in the opinion of the principal investigator, should exclude the patient from the study (patients with pre-existing neuromuscular diseases.
* Allergy or contraindications to any of the anesthetics, NMB agents, or sugammadex.
* Patients with anatomical abnormalities of the hands or arms that prevent proper placement of the sensors for nerve stimulation.
* Limited access to the monitoring area due to surgical positioning.
* Patients with peripheral vascular disease, since it may affect measurement accuracy.

Where it's running

• The Ohio State University Wexner Medical Center
  Columbus, Ohio, United States Recruiting

Study contacts

• Study coordinator: Alberto Uribe, MD
• Email: alberto.uribe@Osumc.edu
• Phone: 6142933559

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• NMTCuff vs standard TOF monitoring during gynecologic oncology surgery

  This study tests whether NMTCuff monitoring can better detect neuromuscular recovery than standard TOF monitoring in women undergoing laparoscopic gynecologic cancer surgery.

  Recruiting Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · Ankara · NCT07925463

• HRS-9190 vs Rocuronium for Muscle Relaxation During Anesthesia

  This Phase 3 trial tests whether HRS-9190 can provide effective muscle relaxation for intubation and surgery as compared with rocuronium in adults undergoing elective general anesthesia.

  Recruiting at 2 sites Phase 3 Jiangsu HengRui Medicine Co., Ltd. · Changsha, Hunan and 1 other locations · NCT07746726

• Low-Dose Rocuronium Maintenance During Spine Surgery With Intraoperative Monitoring

  This study tests whether keeping a low, controlled amount of rocuronium during spine surgery helps nerve monitoring while improving the surgical field compared to stopping rocuronium after induction.

  Recruiting Bach Mai Hospital · Hanoi, Hanoi · NCT07627750

• Safer muscle relaxant and reversal choice during anesthesia for people with chronic kidney disease

  This trial will try to see if using cisatracurium with neostigmine leads to fewer breathing problems after surgery than using rocuronium with sugammadex in adults who have chronic kidney disease.

  Recruiting Phase 4 The University of Texas Medical Branch, Galveston · Galveston, Texas · NCT07203287

• Comparing muscle responses for monitoring neuromuscular function after surgery

  This study is testing a device to see if it can better monitor muscle function after surgery for patients who have received a specific muscle relaxant.

  Recruiting University of Debrecen · Debrecen, Hajdú-Bihar and 1 other locations · NCT06691204

• Investigating neuromuscular blockade effects on pain after laparoscopic surgery in children

  This study tests if using different amounts of a muscle relaxant during laparoscopic surgery can help reduce pain in children aged 2 months to under 7 years after their operation.

  Recruiting Seoul National University Hospital · Seoul, Seoul · NCT06679569

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.