Investigating neuromuscular blockade effects on pain after laparoscopic surgery in children
Effect of Deep Neuromuscular Blockade on Postoperative Pain in Pediatric Patients Undergoing Laparoscopic Surgery: a Prospective Randomized Controlled Trial
This study tests if using different amounts of a muscle relaxant during laparoscopic surgery can help reduce pain in children aged 2 months to under 7 years after their operation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 106 (estimated) |
| Ages | 2 Months to 7 Years |
| Sex | All |
| Sponsor | Seoul National University Hospital Academic / other |
| Locations | 1 site (Seoul, Seoul) |
| Trial ID | NCT06679569 on ClinicalTrials.gov |
What this trial studies
This study examines how different levels of neuromuscular blockade affect postoperative pain in pediatric patients aged over 2 months to under 7 years who are undergoing laparoscopic surgery with general anesthesia. Participants will receive either a low or high dose of rocuronium via continuous infusion during their procedure. The goal is to determine if the degree of neuromuscular blockade can influence pain management outcomes in this population. The findings could provide insights into optimizing anesthesia practices for young patients.
Who should consider this trial
Good fit: Ideal candidates are pediatric patients aged over 2 months to under 7 years scheduled for laparoscopic surgery under general anesthesia.
Not a fit: Patients undergoing emergency surgery or those with chronic pain conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for pediatric patients after surgery.
How similar studies have performed: While there may be studies on neuromuscular blockade, this specific investigation into its impact on postoperative pain in pediatric patients is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pediatric patients aged over 2 months to under 7 years scheduled for laparoscopic surgery under general anesthesia. * American Society of Anesthesiologists (ASA) Physical Status Classification I, II, or III. Exclusion Criteria: * Patients undergoing emergency surgery. * Patients with chronic pain or currently taking analgesics for chronic pain. * Known hypersensitivity to general anesthetic agents or analgesics. * Patients with underlying cardiovascular disease. * Patients with neuromuscular disorders. * Any other condition that, in the investigator's judgment, would make the patient unsuitable for participation in the study.
Where this trial is running
Seoul, Seoul
- Snuch — Seoul, Seoul, South Korea (Recruiting)
Study contacts
- Study coordinator: Clinical Assistant
- Email: snuh.pedane@gmail.com
- Phone: 82-2-2072-3664
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.