Investigating neuromuscular blockade effects on pain after laparoscopic surgery in children
Official title: Effect of Deep Neuromuscular Blockade on Postoperative Pain in Pediatric Patients Undergoing Laparoscopic Surgery: a Prospective Randomized Controlled Trial
Run by Seoul National University Hospital · NCT06679569 · Data updated 2026-11-12
This study tests if using different amounts of a muscle relaxant during laparoscopic surgery can help reduce pain in children aged 2 months to under 7 years after their operation.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 2 Months to 7 Years |
| Sex | All |
| Enrollment | 106 (estimated) |
| Sponsor | Seoul National University Hospital Academic / other |
| Locations | 1 site (Seoul, Seoul) |
| Status | Recruiting |
| Started | November 6, 2024 |
| Main results expected | November 6, 2026 |
| Study ends | November 7, 2026 |
| Registry record updated | May 13, 2025 |
| Trial ID | NCT06679569 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are pediatric patients aged over 2 months to under 7 years scheduled for laparoscopic surgery under general anesthesia.
✕Probably not a fit
Patients undergoing emergency surgery or those with chronic pain conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study examines how different levels of neuromuscular blockade affect postoperative pain in pediatric patients aged over 2 months to under 7 years who are undergoing laparoscopic surgery with general anesthesia. Participants will receive either a low or high dose of rocuronium via continuous infusion during their procedure. The goal is to determine if the degree of neuromuscular blockade can influence pain management outcomes in this population. The findings could provide insights into optimizing anesthesia practices for young patients.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for pediatric patients after surgery.
How similar studies have gone: While there may be studies on neuromuscular blockade, this specific investigation into its impact on postoperative pain in pediatric patients is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pediatric patients aged over 2 months to under 7 years scheduled for laparoscopic surgery under general anesthesia. * American Society of Anesthesiologists (ASA) Physical Status Classification I, II, or III. Exclusion Criteria: * Patients undergoing emergency surgery. * Patients with chronic pain or currently taking analgesics for chronic pain. * Known hypersensitivity to general anesthetic agents or analgesics. * Patients with underlying cardiovascular disease. * Patients with neuromuscular disorders. * Any other condition that, in the investigator's judgment, would make the patient unsuitable for participation in the study.
Where it's running
-
Snuch
Seoul, Seoul, South Korea Recruiting
Study contacts
- Study coordinator: Clinical Assistant
- Email: snuh.pedane@gmail.com
- Phone: 82-2-2072-3664
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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HRS-9190 vs Rocuronium for Muscle Relaxation During Anesthesia
This Phase 3 trial tests whether HRS-9190 can provide effective muscle relaxation for intubation and surgery as compared with rocuronium in adults undergoing elective general anesthesia.
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Two EMG Monitors for Deep NMB During Robotic/Thoracic Surgery
This study tests whether two quantitative EMG monitors (TetraGraph and TwitchView) can better maintain deep neuromuscular blockade during abdominal and thoracic surgery by comparing diaphragmatic movements and breath-initiation events in the same patient.
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Low-Dose Rocuronium Maintenance During Spine Surgery With Intraoperative Monitoring
This study tests whether keeping a low, controlled amount of rocuronium during spine surgery helps nerve monitoring while improving the surgical field compared to stopping rocuronium after induction.
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Safer muscle relaxant and reversal choice during anesthesia for people with chronic kidney disease
This trial will try to see if using cisatracurium with neostigmine leads to fewer breathing problems after surgery than using rocuronium with sugammadex in adults who have chronic kidney disease.
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Comparing muscle responses for monitoring neuromuscular function after surgery
This study is testing a device to see if it can better monitor muscle function after surgery for patients who have received a specific muscle relaxant.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.