Comparing muscle responses for monitoring neuromuscular function after surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of the TetraGraph device in monitoring two muscle groups, the adductor pollicis and the abductor digiti minimi, to assess neuromuscular blockade and recovery following the use of rocuronium during elective surgeries. It aims to identify differences in muscle sensitivity to neuromuscular blocking agents and reversal agents by measuring electrical activity in these muscles through electromyography. The study addresses challenges in monitoring due to patient positioning and involuntary movements, providing a potentially reliable method for detecting residual neuromuscular blockade in postoperative patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age \> or = 18 years old
* Patients willing to participate and provide an informed consent
* Patients undergoing elective surgical procedures that require use of NMBA agents (rocuronium) administered intraoperatively.

Exclusion Criteria:

* Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury.
* Patients with systemic neuromuscular diseases such as myasthenia gravis.
* Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents, i.e., severe renal impairment or end-stage liver disease.
* Patients having surgery that would involve prepping the arm into the sterile field.
* Patients receiving a rapid sequence induction.
* Patients allergic to rocuronium or sugammadex.

Where it's running

• University of Debrecen, Department of Anesthesiology and Intensive Care
  Debrecen, Hajdú-Bihar, Hungary Recruiting
• University of Debrecen, Debrecen, Hajdú-Bihar 4008
  Debrecen, Hungary Completed

Study contacts

• Study coordinator: György NAGY, MD
• Email: gynagy1986@gmail.com
• Phone: +36304354064

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.