The FLORA project: looking for endometrium microbes linked to chronic endometritis and pregnancy success

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study explores whether the endometrial microbiome is associated with chronic endometritis and fertility outcomes in women planning IVF/ICSI. Researchers will analyze diagnostic hysteroscopy samples to characterize microbial composition and inflammation markers using the center’s scoring system for plasma cells. The goal is to see if specific microbial patterns correlate with endometritis and implantation success. Participation is limited to women scheduled for IVF/ICSI at Universitair Ziekenhuis Brussel who have a diagnostic hysteroscopy as part of their treatment workup.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women planned for IVF/ICSI treatment at Brussels IVF (UZ Brussel)
* Women who undergo a diagnostic hysteroscopy in preparation of their treatment

Exclusion criteria:

* If an interventional instead of a diagnostic hysteroscopy in planned
* In the occurence If a previous history of chronic endometritis and the use of antibiotics in the last 3 months.

Where it's running

• Universitair Ziekenhuis Brussel
  Brussels, Belgium Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.