Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Anterior Knee Nerves Block vs Femoral Nerve Block for Knee Arthroscopy

Official title: Comparison of Anterior Nerves of the Knee (ANK) Block and Femoral Nerve Block on Intraoperative Hemodynamics and Postoperative Analgesic Efficacy in Patients Undergoing Knee Arthroscopy: A Prospective, Randomized, Double-Blind Study

Run by Van Training and Research Hospital · NCT07910500 · Data updated 2026-11-12

This trial tests whether an anterior nerves of the knee (ANK) block provides similar pain relief to a femoral nerve block after knee arthroscopy in adults, aiming to reduce quadriceps weakness.

More Postoperative Pain trials

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment70 (estimated)
SponsorVan Training and Research Hospital
Government
Locations1 site (Van)
StatusRecruiting
StartedOctober 19, 2026
Main results expectedMarch 15, 2027
Study endsMarch 15, 2027
Registry record updatedNovember 2, 2026
Trial IDNCT07910500 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18–65 with ASA I–II scheduled for elective knee arthroscopy under spinal anesthesia.

Probably not a fit

Patients may not experience adequate analgesia or may have adverse reactions related to regional anesthesia.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized, single-blind study, adults aged 18–65 undergoing elective knee arthroscopy under spinal anesthesia receive either an ultrasound-guided ANK block or a ultrasound-guided femoral nerve block before surgery. Both blocks use 20 mL of 0.25% bupivacaine, followed by standard spinal anesthesia and routine postoperative rescue analgesia. Pain scores, analgesic consumption, hemodynamics, and time to first mobilization are collected for up to 24 hours, with safety monitoring for block-related complications. The anesthesiologist performing the block is not blinded, but patients and outcome assessors are blinded to group assignment.

Why it matters

Potential benefit: If successful, ANK block could provide effective knee analgesia with less quadriceps weakness, potentially improving early mobilization.

How similar studies have gone: Previous work has explored motor-sparing nerve blocks and demonstrated feasibility; this study tests a newer ANK approach in a randomized setting.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

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Inclusion Criteria:

* Age 18 to 65 years
* American Society of Anesthesiologists (ASA) physical status I-II
* Scheduled for elective knee arthroscopy
* Surgery performed under spinal anesthesia
* Written informed consent

Exclusion Criteria:

* Refusal to participate
* Allergy to local anesthetics or study analgesics
* Infection at the block site
* Coagulopathy or anticoagulant therapy
* Pre-existing neurological deficit or motor weakness in the operated limb
* Chronic pain or regular opioid use
* Inability to cooperate with pain assessment
* Emergency surgery
* Contraindication to spinal anesthesia

Exclusion Criteria:

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Where it's running

  • University of Health Sciences, Van Training and Research Hospital
    Van, Turkey (Türkiye)
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.