Spinal anesthesia with intrathecal morphine vs PENG block (with or without dexamethasone) for hip replacement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter randomized trial compares three regional anesthesia strategies used with spinal anesthesia for elective hip replacement in adults 60 and older. Participants are assigned 1:1:1 to receive spinal anesthesia with intrathecal morphine, a spinal plus PENG block, or a spinal plus PENG block with dexamethasone. All groups use ropivacaine for the spinal component, and intrathecal morphine is used in the control group as part of routine care. The study aims to evaluate postoperative pain, opioid requirements, side effects, and recovery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 60 to 100 years
* Scheduled for elective total hip arthroplasty
* American Society of Anesthesiologists (ASA) physical status I-III
* Ability to understand the study procedures and provide written informed consent

Exclusion Criteria:

* Known allergy or hypersensitivity to ropivacaine, morphine, or dexamethasone
* Coagulation disorders or ongoing anticoagulant therapy contraindicating spinal anesthesia or regional nerve blocks
* Infection at the site of spinal or peripheral nerve block injection
* Pre-existing neurological disorders affecting sensory or motor function
* Severe hepatic or renal insufficiency
* Chronic opioid use for more than 3 months prior to surgery
* Refusal or inability to provide informed consent

Where it's running

• Poznan University of Medical Sciences
  Poznan, Poland Recruiting

Study contacts

• Study coordinator: Malgorzata Reysenr, MD PhD
• Email: mreysner@ump.edu.pl
• Phone: 608762068

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Preoperative Fasting to Shape the Gut with Hip Replacement

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.