PENG Block or Periarticular Injection for Hip Surgery in Older Adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, three-arm trial compares postoperative analgesia strategies in older adults undergoing hip surgery. Participants are assigned to receive either the PENG block alone, the PENG block plus periarticular injection, or periarticular injection alone. The goal is to determine which approach provides superior pain relief without compromising motor function, enabling earlier mobilization and potentially reducing opioid use and related complications. The study focuses on patients 65 years and older with hip procedures and standard ASA I-III status, using structured pain assessments and safety monitoring. Recruitment and execution are centered at Poznan University of Medical Sciences in Poland.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 65 years or older
* Scheduled for elective or emergency hip surgery (e.g., hip fracture fixation or hip arthroplasty)
* ASA physical status I-III
* Ability to communicate pain intensity using the NRS scale
* Written informed consent obtained from the patient or legal representative

Exclusion Criteria:

* Patient refusal or inability to provide informed consent
* Allergy, intolerance, or contraindication to any study medication: ropivacaine
* Pre-existing neurological deficit or neuropathy of the affected limb
* Coagulopathy (INR \>1.5, platelets \<100,000/µL) or current therapeutic anticoagulation that contraindicates regional anesthesia
* Infection at or near the injection site
* Severe hepatic or renal impairment
* History of chronic opioid use (daily opioids \>30 days before surgery)
* Cognitive impairment or delirium precluding reliable pain assessment
* BMI \> 40 kg/m² (if you want to exclude for technical difficulty)
* Patients receiving another regional nerve block for hip surgery
* Pregnancy or breastfeeding
* Participation in another interventional clinical trial within 30 days

Where it's running

• Poznan University of Medical Sciences
  Poznan, Poland Recruiting

Study contacts

• Study coordinator: Malgorzata Reysner, MD PhD
• Email: mreysner@ump.edu.pl
• Phone: +48 61 873 83 03

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Spinal anesthesia with intrathecal morphine vs PENG block (with or without dexamethasone) for hip replacement

  In people aged 60 and older undergoing total hip arthroplasty, this study tests whether three anesthesia approaches provide better pain control and fewer side effects: spinal with intrathecal morphine, spinal with a PENG block, or spinal with a PENG block plus dexamethasone.

  Recruiting Poznan University of Medical Sciences · Poznan · NCT07584200

• PENG nerve block plus dexmedetomidine for hip surgery pain in older adults

  This will test whether adding a small dose of dexmedetomidine to a PENG nerve block gives longer, better pain relief and reduces opioid need for people 65 and older having hip surgery.

  Recruiting Poznan University of Medical Sciences · Poznan · NCT07327372

• Ceramic hip resurfacing vs total hip arthroplasty for hip OA

  This trial tests whether ceramic hip resurfacing helps people with hip OA walk farther each day than a modern total hip replacement.

  Recruiting Danderyd Hospital · Danderyd · NCT07839403

• Dexmedetomidine during hip replacement to modulate nerves and inflammation

  A randomized, placebo-controlled study tests whether intravenous dexmedetomidine given during spinal anesthesia with a PENG nerve block can help regulate the body's stress and inflammatory response and improve recovery after hip replacement.

  Recruiting Poznan University of Medical Sciences · Poznan · NCT07743853

• Preoperative Fasting to Shape the Gut with Hip Replacement

  This trial tests whether a 20-day preoperative fasting plan can lower inflammatory signals and broaden gut microbes in adults undergoing total hip arthroplasty.

  Recruiting Charite University, Berlin, Germany · Berlin, State of Berlin · NCT07651462

• Mako-MORE Registry: Real-world Outcomes After Knee and Hip Arthroplasty

  This registry collects real-world data from adults having hip or knee joint replacement with or without the Mako robotic system to see how they do over up to five years.

  Recruiting at 2 sites Stryker Orthopaedics · Jacksonville, Florida and 4 other locations · NCT07647354

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.