Ceramic hip resurfacing vs total hip arthroplasty for hip OA

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

MOVE-HIP is a multicenter randomized study comparing ceramic-on-ceramic hip resurfacing with contemporary total hip arthroplasty in adults with symptomatic hip osteoarthritis who could receive either procedure. Participants are randomized 1:1 and kept blinded to allocation where feasible through 24 months, with objective activity measured by wearable devices during 7-day periods at 3, 12, and 24 months. The study also includes a separate observational cohort of eligible patients who decline randomization, analyzed separately. Primary outcome is the adjusted difference in mean daily walking distance between groups from 3 to 24 months; secondary outcomes include step count, patient-reported outcomes, radiographs, perioperative metrics, complications, implant survival, and health-economic outcomes, with long-term follow-up planned up to 10 years.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years or older.
* Symptomatic hip osteoarthritis for which primary hip arthroplasty is indicated according to routine clinical practice.
* Considered suitable for both ceramic hip resurfacing arthroplasty and uncemented total hip arthroplasty by the treating surgeon.
* Ability and willingness to comply with study procedures, including patient-reported outcome measures, radiographs, registry linkage, and repeated wearable monitoring.
* Provision of written informed consent.

Exclusion Criteria:

* Anatomical or pathological conditions that clearly preclude hip resurfacing arthroplasty or total hip arthroplasty, including severe deformity requiring non-standard implants or techniques.
* Insufficient femoral head or acetabular bone quality, including large or multiple cysts, advanced femoral head necrosis, severe osteopenia, or osteoporosis where this would contraindicate hip resurfacing arthroplasty.
* Body mass index greater than 40 kg/m\^2.
* Requirement for specialized implants outside routine study procedures.
* Medical comorbidity rendering the patient unfit for surgery.
* Cognitive impairment, severe psychiatric disease, alcohol or substance abuse, language barrier, or other reason judged to prevent informed consent or compliance with follow-up.
* Inability to complete patient-reported outcome measures or to participate in wearable monitoring.

Where it's running

• Danderyd Hospital
  Danderyd, Sweden Recruiting

Study contacts

• Principal investigator: Olof Sköldenberg, MD, PhD — Danderyd Hospital, Region Stockholm / Karolinska Institutet
• Study coordinator: Olof Sköldenberg, MD, PhD
• Email: olof.skoldenberg@ki.se
• Phone: +46 8 123 572 45

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.