Rise & Thrive: a community-engagement program to help youth manage stress and depressive symptoms
Official title: Rise & Thrive: Community-Engagement Intervention to Address Chronic Stress and Prevent Depression in Adolescents and Young Adults
Run by Ann & Robert H Lurie Children's Hospital of Chicago · NCT07554326 · Data updated 2026-11-12
A group-based program tests whether community engagement activities can help Black and/or Hispanic/Latine youth aged 15-20 see reductions in depressive symptoms.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 15 Years to 20 Years |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Ann & Robert H Lurie Children's Hospital of Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Status | Recruiting |
| Started | June 9, 2026 |
| Main results expected | December 1, 2028 |
| Study ends | December 29, 2029 |
| Registry record updated | October 22, 2026 |
| Trial ID | NCT07554326 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are 15-20 year olds who identify as Black and/or Hispanic/Latine, speak English, and can attend in-person sessions in Chicago.
✕Probably not a fit
Youth who do not experience depressive symptoms or who cannot participate in in-person sessions may see limited benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This phase II randomized trial compares a Rise Together community engagement intervention to Adulting 101 life skills training in 300 youths aged 15-20 in Chicago. Participants are block-stratified by race/ethnicity and gender and then randomized to five half-day sessions of either community engagement or life skills training. The study measures depressive symptoms and psychological distress at baseline and multiple follow-ups up to 24 months, along with other health-related outcomes linked to chronic stress. The goal is to determine if a non-medication, behavioral intervention can reduce depressive symptoms and related distress in stressed youth from minority backgrounds. Recruitment focuses on in-person participation within the hospital’s catchment area and affiliated centers.
Why it matters
Potential benefit: If successful, participants and similar youth could experience fewer depressive symptoms and better coping with stress.
How similar studies have gone: Prior non-pharmacologic, youth-focused behavioral interventions have shown promise in reducing distress, though the specific community-engagement approach is relatively novel in this demographic.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. 15-20 years old 2. Identify as Black and/ or Hispanic/Latine 3. Speak English Exclusion Criteria: 1. Younger than 15 years old, or older than 20 years old 2. Unable to attend the in-person sessions 3. Non-fluent English speaker 4. Do not identify as Black or Hispanic/Latine
Where it's running
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Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, United States Recruiting
Study contacts
- Principal investigator: Elan C Hope, PhD — Policy Research Associates
- Study coordinator: Nia J Heard Garris, MD, MBA, MSc
- Email: nheardgarris@luriechildrens.org
- Phone: 3122272664
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.