Asprosin and miRNA Profiles in Young Women with Metabolic Syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational, cross-sectional case-control study enrolling young women aged 18 to 35. Researchers will measure serum asprosin concentration, six circulating microRNAs, and various metabolic and lifestyle factors from a single study visit. The goal is to see if the biomarker panel can distinguish those with metabolic syndrome from healthy controls and to explore relationships with components such as obesity, insulin resistance, and dyslipidemia. Secondary goals include comparing body composition, insulin resistance indices, lipid profiles, physical activity, diet, sleep quality, stress, and quality of life between groups. The study uses biomarker assays and questionnaire-based assessments to analyze potential diagnostic value and associations with metabolic risk factors.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female sex
* Age 18 to 35 years
* Regular menstrual cycle
* Not engaged in competitive sports training in any discipline
* Non-smoker
* No alcohol abuse
* No continuous pharmacotherapy, with the exception of treatment for diabetes and/or antihypertensive treatment; no use of hormonal contraception
* Written informed consent for study participation and processing of personal data

Exclusion Criteria:

* Age outside the range of 18 to 35 years
* Irregular menstrual cycle
* Pregnancy or breastfeeding
* Continuous pharmacotherapy for indications other than diabetes and/or hypertension, including any form of hormonal contraception (oral, transdermal, vaginal, implant, injectable or intrauterine)
* Competitive sports training in any discipline
* Current smoking
* Alcohol abuse
* Lack of written informed consent for study participation and processing of personal data

Where it's running

• Institute of Medicine, University of Applied Sciences in Nowy Targ, Kokoszków 71, 34-400 Nowy Targ, Poland
  Nowy Targ, Lesser Poland Voivodeship, Poland Recruiting

Study contacts

• Principal investigator: Małgorzata Kantorowicz, Ph. D. — University of Applied Sciences in Nowy Targ
• Study coordinator: Małgorzata Kantorowicz, Ph.D.
• Email: sknmedicus@ans-nt.edu.pl
• Phone: +48 662 251 012

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.