Clinical trial Recruiting at 1 site Interventional Ages 13 to 17

Low-Calorie Diet in adolescents with Familial Mediterranean Fever and metabolic syndrome

Official title: Metabolic Syndrome Resposne to Dietary Limitations in Familial Mediterranean Fever in Adolescents

Run by Cairo University · NCT07833007 · Data updated 2026-11-12

A group of adolescents with both FMF and metabolic syndrome will try a low-calorie diet for 3 months to see if it helps manage metabolic symptoms.

Quick facts

Study typeInterventional
Ages13 Years to 17 Years
SexAll
Enrollment40 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Giza, Dokki)
StatusRecruiting
StartedAugust 10, 2026
Main results expectedDecember 15, 2026
Study endsDecember 15, 2026
Registry record updatedSeptember 22, 2026
Trial IDNCT07833007 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adolescents with both Familial Mediterranean Fever and metabolic syndrome who do not have significant cardiac, respiratory, or tumor conditions.

Probably not a fit

Individuals with FMF who do not have metabolic syndrome or those unable to adhere to a dietary program may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study investigates whether a low-calorie diet can improve metabolic syndrome features in adolescents with Familial Mediterranean Fever. Forty participants will be randomized into a diet-change group and a control group that maintains their usual eating habits. The diet group will follow a reduced-calorie regimen for three months, with outcomes likely including changes in weight, blood sugar, cholesterol, and inflammatory markers. The trial is conducted at Cairo University in Giza/Dokki, led by the institution with no listed collaborators.

Why it matters

Potential benefit: If successful, participants may experience improvements in metabolic risk factors and overall health, potentially reducing FMF-related complications.

How similar studies have gone: There is limited published evidence on dietary interventions specifically for adolescents with FMF and metabolic syndrome, making this approach relatively novel in this population.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* metabolic syndrome
* familial mediterreanean fever

Exclusion Criteria:

* cardiac diseases
* repsiratory diseases
* tumors

Where it's running

  • Cairo University
    Giza, Dokki, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.