Low-Calorie Diet in adolescents with Familial Mediterranean Fever and metabolic syndrome
Official title: Metabolic Syndrome Resposne to Dietary Limitations in Familial Mediterranean Fever in Adolescents
Run by Cairo University · NCT07833007 · Data updated 2026-11-12
A group of adolescents with both FMF and metabolic syndrome will try a low-calorie diet for 3 months to see if it helps manage metabolic symptoms.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 13 Years to 17 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Giza, Dokki) |
| Status | Recruiting |
| Started | August 10, 2026 |
| Main results expected | December 15, 2026 |
| Study ends | December 15, 2026 |
| Registry record updated | September 22, 2026 |
| Trial ID | NCT07833007 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adolescents with both Familial Mediterranean Fever and metabolic syndrome who do not have significant cardiac, respiratory, or tumor conditions.
✕Probably not a fit
Individuals with FMF who do not have metabolic syndrome or those unable to adhere to a dietary program may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study investigates whether a low-calorie diet can improve metabolic syndrome features in adolescents with Familial Mediterranean Fever. Forty participants will be randomized into a diet-change group and a control group that maintains their usual eating habits. The diet group will follow a reduced-calorie regimen for three months, with outcomes likely including changes in weight, blood sugar, cholesterol, and inflammatory markers. The trial is conducted at Cairo University in Giza/Dokki, led by the institution with no listed collaborators.
Why it matters
Potential benefit: If successful, participants may experience improvements in metabolic risk factors and overall health, potentially reducing FMF-related complications.
How similar studies have gone: There is limited published evidence on dietary interventions specifically for adolescents with FMF and metabolic syndrome, making this approach relatively novel in this population.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * metabolic syndrome * familial mediterreanean fever Exclusion Criteria: * cardiac diseases * repsiratory diseases * tumors
Where it's running
-
Cairo University
Giza, Dokki, Egypt Recruiting
Study contacts
- Principal investigator: Ali MA Ismail, PHD — Cairo University
- Study coordinator: Ali Ismail, PhD
- Email: ali.mohamed@pt.cu.edu.eg
- Phone: +201005154209
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.