Sponsor or institution
Clinical trials and research at Ann & Robert H Lurie Children's Hospital of Chicago
As of November 12, 2026, Find a Trial lists 40 clinical trials run by Ann & Robert H Lurie Children's Hospital of Chicago that are recruiting, in United States. By phase: Phase 1 (2), Phase 2 (2), Phase 1/2 (1), Early Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 40Clinical trials
- 1Country
Newest trials
All recruiting trials (40)
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Postoperative Atrial Pacing in Children After Heart Surgery
This study tests whether briefly raising a child’s heart rate after heart surgery improves blood flow and oxygen delivery by using temporary atrial pacing at 10 or 20 beats per minute above the child’s natural rate.
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Rise & Thrive: a community-engagement program to help youth manage stress and depressive symptoms
A group-based program tests whether community engagement activities can help Black and/or Hispanic/Latine youth aged 15-20 see reductions in depressive symptoms.
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Side-by-Side Testing of SPARCS and the Unified Protocol for Youth with Chronic Illness and Trauma
This trial tests whether two trauma-focused therapies (SPARCS and the Unified Protocol) help kids and teens with chronic medical conditions feel less trauma-related distress and function better, delivered in group or individual formats.
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Support for caregivers after a child's emergency visit for suicidal thoughts or behaviors
This pilot test compares follow-up phone calls and automated MyChart messages to usual care for caregivers of 10–17-year-olds discharged from the ER after suicidal thoughts or behaviors.
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Bowel continence across life for people with spina bifida
This project will test whether retrograde (through the anus) or antegrade (through a tube into the colon) enema programs work better to prevent bowel accidents and improve independence for people with spina bifida ages 5 and up who are starting or switching an enema program.
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Hospital-to-home support (H-HOPE) for infants with congenital defects after neonatal surgery and their parents
This program tests whether H-HOPE helps infants born with congenital defects who need neonatal surgery — and their parents — improve feeding, growth, early development, and parental mental health.
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Our Voices Matter: racial-justice activism program to reduce depression in Black and Latinx youth
This program tests whether participating in racial-justice activism can reduce depressive symptoms and stress-related physical risk in Black and Latinx youth ages 15-20.
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Caring Contacts via Text Messages for suicidal adolescents after emergency department discharge
This study tests whether brief, hopeful text messages can help adolescents with suicidal thoughts or behaviors after leaving the emergency department, alongside usual care.
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Antibiotic strategies for young children with pneumonia in outpatient care
This trial will see if a 'watch-and-wait' Safety Net Antibiotic Prescribing (SNAP) approach can safely reduce antibiotic use compared with immediate antibiotics in children aged 12 months to under 6 years with mild community-acquired pneumonia.
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Combining MAPK inhibitors with anti-PD1 therapy for pediatric gliomas with BRAF alterations
This study is testing if combining two cancer drugs with a new therapy can help children with certain types of brain tumors feel better and have more treatment options.
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Reducing diabetes distress in teenagers
This study is testing a new program to help teenagers with Type 1 Diabetes feel less stressed about their condition by comparing in-person and online support sessions.
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Freezing gonadal tissue to help preserve fertility in children with sex development disorders
This study is testing whether freezing and storing gonadal tissue can help children with sex development disorders keep their fertility for the future.
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Collecting data on Congenital Central Hypoventilation Syndrome
This study is gathering information about Congenital Central Hypoventilation Syndrome from different hospitals and families to better understand the condition and improve future treatments.
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Testing a medication for children with chronic kidney disease
This study is testing if a new kidney medication can help children with chronic kidney disease feel better and improve their health over three months.
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Using Fitbit to detect infections in children after appendectomy
This study tests if using Fitbit data can help doctors spot infections early in children recovering from appendix surgery.
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Using SGLT2 inhibitors to treat fatty liver disease in obese adolescents
This study is testing if a medication called empagliflozin can help obese teenagers with fatty liver disease improve their liver health and overall well-being.
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Using Cytalux for better cancer surgery in children
This study is testing if a special imaging agent called Cytalux can help doctors find and remove lung tumors more effectively during surgery in children with cancer.
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Comparing two support interventions for parents after a child's unexpected death
This study is testing two different support programs to see which one helps parents cope better after the unexpected death of their child under 25.
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Improving communication skills in anesthesiology residents
This study is testing if a special training method can help anesthesiology residents improve their communication skills better than traditional learning methods.
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Using brain imaging to improve language outcomes for children with hearing loss
This study is testing a new way to use brain scans to help predict and improve language skills in children with hearing loss who are getting cochlear implants.
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Soy isoflavones for infants at risk of asthma
This study is testing if giving soy isoflavones to infants at high risk for asthma can help reduce their chances of developing the condition compared to a placebo.
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Fetoscopic procedure for severe congenital diaphragmatic hernia in fetuses
This study is testing a new procedure that places a balloon in the trachea of unborn babies with severe congenital diaphragmatic hernia to see if it helps their lungs grow and improves their chances of survival after birth.
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Comparing surgery and medications for treating Lennox-Gastaut syndrome
This study is testing whether surgery or extra medications work better for people with Lennox-Gastaut syndrome to help reduce seizures and improve their daily lives.
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Understanding long-term effects of breathing patterns in preterm infants
This study looks at how breathing problems in preterm babies might affect their chances of developing asthma, sleep issues, and learning difficulties as they grow up.
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Freezing ovarian tissue to preserve fertility in young cancer patients
This study is testing whether freezing ovarian tissue can help young cancer patients preserve their fertility for the future after they undergo treatments like chemotherapy or radiation.
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Freezing ovarian tissue in young girls at risk of infertility
This study is testing if freezing ovarian tissue from young girls before they start cancer treatments can help them have babies later in life.
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Registry for Eosinophilic Gastrointestinal Disorders
This study is collecting information from people with Eosinophilic Gastrointestinal Disorders to better understand their symptoms and improve treatments for them.
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Comparing treatments for children's wrist fractures
This study is testing whether treating children's wrist fractures with a special procedure works better than just putting them in a cast to see which method helps them heal and function better.
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Comparing cast versus surgery for treating elbow fractures in children
This study is testing whether treating elbow fractures in kids with surgery works better than using a cast to see which method helps them heal and function better.
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Understanding weight regain in youth with obesity
This study is testing how meal replacement therapy and counseling can help young people who have lost weight understand and prevent regaining it by looking at the role of hormones.
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Donation of pediatric tumor tissues and cells after death
This study is trying to collect tumor tissues and cells from children who have passed away to help create better models for studying pediatric cancers and testing new treatments.
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Combination immunotherapy for newly diagnosed DIPG and DMG
This study is testing a new combination of a cancer vaccine and other treatments to see if it can help children with newly diagnosed DIPG and DMG fight their tumors better after finishing radiation therapy.
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Evaluating ACL and ALL Reconstruction in Children
This study is testing if kids who have surgery for a knee ligament injury do better when they have two ligaments fixed instead of just one.
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Using wearable sensors to monitor vital signs in ICU patients
This study is testing new wearable sensors to see if they can accurately monitor vital signs in ICU patients compared to regular monitoring devices.
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Understanding AMH Levels in Healthy Girls
This study is trying to find out the normal levels of a hormone called AMH in girls aged 0-18 to help understand their reproductive health and fertility options, especially for young cancer patients.
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Collecting ovarian tissue samples from girls undergoing surgery
This study is collecting leftover ovarian tissue from girls and women aged 0-18 who are having surgery to see how different ovarian conditions impact fertility.
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Assessing neurocognition in patients with congenital central hypoventilation syndrome
This study is trying to see how a special set of tests can help understand the thinking and memory skills of people with congenital central hypoventilation syndrome and what factors might affect their cognitive health.
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International registry for Rapid-onset Obesity with Hypothalamic Dysfunction
This study is creating a global registry to gather health information from people with Rapid-onset Obesity with Hypothalamic Dysfunction (ROHHAD) to help doctors better understand and manage the condition.
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International registry for Congenital Central Hypoventilation Syndrome
This study is creating a global registry to collect information about people with Congenital Central Hypoventilation Syndrome to better understand how the condition affects them over time.
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Evaluating treatment options for type I open fractures in children
This study tests if children with type I open fractures can be treated safely in the emergency room without surgery, comparing this approach to the usual surgical treatment.
Quick answers
How many clinical trials run by Ann & Robert H Lurie Children's Hospital of Chicago are recruiting right now?
40, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 2, Phase 2: 2, Phase 1/2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.