Cesarean Anesthesia Blood Gas
Official title: Effects of Spinal and General Anesthesia Techniques on Maternal-Fetal Blood Gas Gradients and Fetal Carboxyhemoglobin Levels in Cesarean Delivery: A Prospective Observational Cohort Study
Run by Bagcilar Training and Research Hospital · NCT07861633 · Data updated 2026-11-12
This study tests and compares blood gas parameters in moms and babies when cesarean deliveries are done with spinal vs general anesthesia.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 134 (estimated) |
| Sponsor | Bagcilar Training and Research Hospital Government |
| Locations | 1 site (Istanbul, Istanbul) |
| Status | Recruiting |
| Started | October 1, 2026 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | October 8, 2026 |
| Trial ID | NCT07861633 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adult women undergoing cesarean delivery who will receive either spinal or general anesthesia at Bagcilar Training and Research Hospital.
✕Probably not a fit
Patients whose cesarean delivery is converted from spinal to general anesthesia or who do not meet the specific inclusion criteria may not benefit from any findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective observational cohort study will measure maternal venous blood gas values before anesthesia and umbilical arterial blood gas values after delivery in women undergoing cesarean delivery with either spinal or general anesthesia. The investigators will compare pH, pCO2, pO2, bicarbonate, base excess, lactate, and fetal carboxyhemoglobin levels between the two anesthesia techniques. Additional outcomes include maternal-fetal blood gas gradients, Apgar scores, NICU requirements, and the association between smoking exposure and fetal carboxyhemoglobin. The study will help clarify how anesthesia type may influence neonatal physiology at birth without manipulating treatment assignments.
Why it matters
Potential benefit: Findings could inform anesthesia choice and perioperative care to optimize newborn blood gas status and short-term outcomes.
How similar studies have gone: Other studies have explored blood gas changes with different anesthesia techniques, but this exact comparison in cesarean delivery is relatively specific and adds new observational data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult women undergoing cesarean delivery at the study center. * Patients receiving spinal or general anesthesia for cesarean delivery. Exclusion Criteria: * Patients who are not eligible for participation according to the study protocol. * Patients in whom spinal anesthesia is converted to general anesthesia because of inadequate spinal block and pain during surgery.
Where it's running
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Bağcılar Training and Research Hospital
Istanbul, Istanbul, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Ali KAHVECİOĞLU, MD — University of Health Sciences, Bağcılar Training and Research Hospital
- Study coordinator: Ali KAHVECİOĞLU, MD
- Email: ali.kahveci92@gmail.com
- Phone: +90 5549134317
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Dexmedetomidine or Clonidine added to spinal anesthesia for cesarean delivery
This study tests whether adding dexmedetomidine or clonidine to spinal anesthesia for cesarean delivery improves intraoperative comfort and analgesia.
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Buprenorphine vs morphine for pain control after cesarean delivery
This study tests whether intrathecal buprenorphine provides better postcesarean pain relief than morphine for women undergoing a planned cesarean delivery.
-
Restrained vs Gripping Wrist Restraints for Cesarean Delivery
This study tests whether a soft wrist-level gripping restraint reduces anxiety for adults having an elective cesarean delivery under spinal or combined spinal-epidural anesthesia.
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Pupil light reflex to predict low blood pressure after spinal anesthesia in cesarean deliveries
Doctors want to see if a quick eye-pupil test done before spinal anesthesia can predict who might develop low blood pressure after a cesarean delivery.
-
Arm versus ankle mean arterial pressure during elective cesarean delivery
This study will see if a blood pressure cuff on the ankle gives similar mean arterial pressure readings to a standard arm cuff in pregnant people having a planned C-section under spinal anesthesia.
-
Topical tranexamic acid to cut blood loss during cesarean delivery
This study tests whether spraying tranexamic acid onto the uterine incision during cesarean delivery can reduce bleeding compared with placebo.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.