Clinical trial Recruiting at 1 site Observational Ages 18 and up Women only

Understanding nausea and vomiting after elective C-sections under spinal anesthesia

Official title: Incidence and Risk Factors of Postoperative Nausea and Vomiting (PONV) During Elective C-Section Under Spinal Anesthesia With Multimodal Antiemetic Prophylaxis

Run by University of Liege · NCT06927830 · Data updated 2026-11-12

This study looks at how often women feel nauseous or vomit after having a planned C-section with spinal anesthesia and what might cause it.

Quick facts

Study typeObservational
Ages18 Years and up
SexWomen only
Enrollment400 (estimated)
SponsorUniversity of Liege
Academic / other
Locations2 sites (Chenée and 1 other locations)
StatusRecruiting
StartedMarch 19, 2025
Main results expectedMarch 2026
Study endsApril 2026
Registry record updatedApril 15, 2025
Trial IDNCT06927830 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients requiring elective cesarean sections at a gestational age greater than 37 weeks with a single fetus.

Probably not a fit

Patients with contraindications to spinal anesthesia or those who have experienced nausea and vomiting in the 24 hours prior to the procedure may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the frequency and risk factors associated with postoperative nausea and vomiting (PONV) in patients undergoing elective cesarean sections with spinal anesthesia. Participants will be monitored for nausea and vomiting in the recovery room and during follow-up visits within the first 24 hours post-surgery. The study will utilize a standard management protocol that includes the administration of intrathecal morphine and multimodal antiemetic prophylaxis. Data collected will help identify the incidence of PONV and the factors that may contribute to its occurrence.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies for preventing nausea and vomiting in patients undergoing cesarean sections.

How similar studies have gone: Previous studies have shown varying success in managing postoperative nausea and vomiting in similar surgical contexts, indicating that this area of research is both relevant and necessary.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Any patient requiring elective caesarean section under spinal anesthesia, at a gestational age \>37 weeks of amenorrhea in the context of a single-fetal pregnancy.

Exclusion Criteria:

Failure to understand the French language; Contraindication to locoregional anesthesia; Nausea and/or vomiting in the 24 hours preceding the procedure; Type 1 or type 2 insulin-requiring non-gestational diabetes; Allergy or contraindication to one of the products used in the usual management protocol; Severe preeclampsia; Height \<150 cm

Where it's running

  • CHU de Liège - site de Notre-Dame des Bruyères
    Chenée, Belgium
    Recruiting
  • Hôpital de la Citadelle - site Citadelle
    Liège, Belgium
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.