Does implant type affect knee alignment when using KUNWU robotic surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-center, randomized, double-blind study evaluating two commercial knee implants—Attune and Persona—used with a novel CT-based KUNWU robotic system for total knee replacement in adults with knee osteoarthritis. Participants are randomly assigned to receive one of the two implants, while patients and outcome assessors remain unaware of the implant choice. All surgeries are performed by a single team using the KUNWU system to follow preoperative CT plans and achieve target alignment. The primary outcome is the accuracy of postoperative knee alignment relative to the preoperative plan; secondary considerations include safety and surgical workflow. Enrollment is limited to eligible adults at The Duchess of Kent Children’s Hospital in Hong Kong, with standard inclusion/exclusion criteria.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years and older.
* Diagnosis of symptomatic knee osteoarthritis requiring total knee replacement.
* Ability to give informed consent.
* Feasibility of using the two types of implants

Exclusion Criteria:

\- Severe radiographic knee OA (Kellgren-Lawrence grade 4) or severe knee pain (VAS\>80mm/100 mm) that could not tolerate further conservative management

Where it's running

• The Duchess of Kent Children's Hospital at Sandy Bay
  Hong Kong, Sandy Bay, Hong Kong Recruiting

Study contacts

• Study coordinator: Chun Man Lawrence Prof. Lau, MBChB, MRCSEd, FRCSEd(Orth), F
• Email: laucml@hku.hk
• Phone: 92646862

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.