Digital Rehab Program for knee OA using multisensory gear and digital twin tech

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study develops and tests a digital rehabilitation platform for knee osteoarthritis and healthy adults that combines a wearable knee brace with sensing, biofeedback, and digital twin technology. Participants may follow home-based exercises guided by therapists, with gait retraining and neuromuscular electrical stimulation components. The program aims to provide objective monitoring, real-time feedback, and personalized adjustments to improve adherence and movement quality outside the clinic. The research is conducted through collaboration between National Taiwan University Hospital and partner institutions, with multiple sites in Taipei. The trial is interventional and leverages multisensory stimulation to support rehabilitation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

(Group A: Healthy Adults)

* Participants aged 20 to 80 years.
* Participants who have no knee discomfort symptoms, such as knee pain or muscle weakness.

(Group B: Patients with Knee Osteoarthritis)

* Participants aged 50 to 80 years.
* Patients diagnosed with knee osteoarthritis, classified as Kellgren-Lawrence grade 1 to grade 3.

Exclusion Criteria:

(Group A and B)

* History of knee or hip surgery.
* Systemic arthritis.
* Neurological disease.
* Malignant tumor.
* Untreated osteomyelitis or immature skeletal development.
* Pregnancy.
* Inflammatory ulcer.
* Deep vein thrombosis.
* Excessively moist wounds.
* Hemophilia.
* Local infection in the treatment or assessment area.
* Acute myocardial infarction.
* Unstable angina.
* Severe aortic stenosis.
* Uncontrolled heart failure.
* Acute pulmonary embolism.
* Acute myocarditis or pericarditis.
* Acute aortic dissection.

Where it's running

• Taipei Tzu Chi Hospital International Medical Service Center
  Taipei, Taiwan Recruiting
• National Taiwan University Hospital
  Taipei, Taiwan Not yet recruiting
• School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University
  Taipei, Taiwan Not yet recruiting

Study contacts

• Study coordinator: Wei-Li Hsu, Ph.D.
• Email: wlhsu@ntu.edu.tw
• Phone: 886-2-3366-8127

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.