Aquatic exercise for knee osteoarthritis and central sensitization
Official title: The Effect of Aquatic Exercise on Central Sensitization and Functional Parameters in Patients With Knee Osteoarthritis: a Randomized Controlled Trial
Run by Kirsehir Ahi Evran Universitesi · NCT07883824 · Data updated 2026-11-12
A water-based exercise program is being tested to see if it helps people aged 40–65 with knee osteoarthritis who also have central sensitization.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 65 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Kirsehir Ahi Evran Universitesi Academic / other |
| Locations | 1 site (Kırşehir, Merkez) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | December 1, 2026 |
| Study ends | February 1, 2027 |
| Registry record updated | November 4, 2026 |
| Trial ID | NCT07883824 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 40–65 with knee osteoarthritis and central sensitization who do not have cognitive impairments or recent knee surgery.
✕Probably not a fit
Participants with cognitive impairment, recent knee surgery, fracture, malignancy, infection, or pregnancy may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study uses standard physical therapy and hydrotherapy to explore whether aquatic exercise can reduce central sensitization and improve functional outcomes in adults with knee osteoarthritis. It will assess changes in pain processing, balance, and quality of life. The trial is conducted at Kirsehir Ahi Evran University in Turkey and involves volunteers meeting specific eligibility criteria. Results could help clarify if water-based exercise benefits this patient group beyond traditional therapy.
Why it matters
Potential benefit: If successful, participants may experience reduced pain sensitivity and better knee function through aquatic exercise.
How similar studies have gone: Previous research in related areas suggests aquatic therapy can help knee OA and pain, but specific effects on central sensitization are less established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Adults aged 40-65 2. Individuals diagnosed with knee osteoarthritis 3. Individuals with no cognitive impairments 4. Volunteers for the study Exclusion Criteria: 1. Individuals who have undergone knee surgery 2. Individuals presenting with signs such as fracture, malignancy, or infection 3. Pregnancy 4. Individuals with cognitive impairments who are unable to express themselves.
Where it's running
-
Kirsehir Ahi Evran University, Kırşehir, Merkez 40100
Kırşehir, Merkez, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Mensure Aslan
- Email: mensure.aa@outlook.com
- Phone: 90 386 280 50 31
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.