Gender-based test of a graded weight-bearing physiotherapy for knee osteoarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study assigns 52 adults with Kellgren-Lawrence grade II–III knee OA to a standardized 6-week physiotherapy program with three supervised sessions per week. It uses sensory stimulation combined with progressive weight-bearing to improve neuromuscular control, balance, and function, and measures pain, function, proprioception, gait, and quality of life at baseline, 3 weeks, and 6 weeks. The trial aims to compare treatment effects between genders while using validated tools (VAS, WOMAC, JPS, 6MWT, SF-36) to capture multiple dimensions of patient-important outcomes. Participants are primary recruited from a single site in Gujar Khan, Pakistan, with specific eligibility and exclusion criteria to ensure safety and relevance. The study is interventional and does not involve a pharmaceutical component.

Why it matters

Who can join: the full rules

Inclusion criteria

* Participants are eligible for inclusion if they meet the following criteria:
* Age between 40 and 60 years.
* Diagnosed with Grade II or Grade III Knee Osteoarthritis according to Kellgren-Lawrence Classification.
* Ability to ambulate independently without assistive devices.
* Mild to moderate pain intensity with a Visual Analogue Scale score less than seven.
* Ability to understand and follow instructions.
* Willingness to participate and provide written informed consent. Exclusion Criteria
* Participants are excluded if they meet any of the following criteria:
* History of knee surgery within the previous six months.
* Neurological disorders affecting balance, gait, or proprioception.
* Severe cardiovascular disease limiting participation in exercise.
* Rheumatoid arthritis or other inflammatory arthritic conditions.
* Severe cognitive impairment.
* Any medical condition that contraindicates participation in rehabilitation exercises.

Where it's running

• T.H.Q hospital
  Gujar Khan, Punjab Province, Pakistan Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.