Oral tizanidine before surgery to calm pain after leg surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults 21 and older undergoing lower limb orthopedic procedures will be randomly assigned to receive oral tizanidine or a placebo before surgery. The study aims to see if the preoperative dose can lessen pain after surgery and improve sleep, potentially reducing opioid needs and related side effects. Outcomes focus on postoperative pain levels and sleep quality, among other perioperative experiences. The trial is sponsored by Tanta University and conducted at Tanta University Hospital in Egypt.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged ≥ 21 years

  * Scheduled for lower limb orthopedic surgery
  * Able to provide informed consent

Exclusion Criteria:

* History of hypersensitivity to tizanidine

  * Pregnancy or breastfeeding
  * Failure of spinal anesthesia or inadequate block.

Where it's running

• tanta University hospital
  Tanta, Gharbia Governorate, Egypt Recruiting

Study contacts

• Study coordinator: Marwa Abogabal, Assistant professor
• Email: Dr_mora1985@med.tanta.edu.eg
• Phone: 0201004190210

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.