Influence of Irrigant Delivery Methods on Postoperative Pain after Root Canal Treatment in Oval Canals
Official title: Influence of Irrigant Delivery Systems on the Incidence of Postoperative Discomfort in Oval Canals : A Randomized Clinical Trial
Run by Minia University · NCT07788027 · Data updated 2026-11-12
This trial tests whether different irrigant delivery and activation methods affect postoperative pain after primary root canal treatment in adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | All |
| Enrollment | 32 (estimated) |
| Sponsor | Minia University Academic / other |
| Locations | 1 site (Minya) |
| Status | Recruiting |
| Started | April 14, 2026 |
| Main results expected | April 1, 2027 |
| Study ends | April 14, 2027 |
| Registry record updated | August 26, 2026 |
| Trial ID | NCT07788027 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18-45 needing primary root canal treatment and in good general health (ASA-1) without recent analgesic or antibiotic use.
✕Probably not a fit
Patients with systemic conditions affecting pain or healing, pregnant or lactating women, or teeth with prior treatment or severe periodontal disease may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares how various irrigation delivery systems and activation methods influence postoperative discomfort in patients undergoing primary root canal treatment. The focus is on delivering sodium hypochlorite effectively to hard-to-reach areas of the root canal while minimizing irritants reaching surrounding tissues. It acknowledges anatomy-related challenges and potential pain outcomes associated with different activation techniques. The trial evaluates whether newer or more aggressive irrigation approaches increase or reduce postoperative pain compared with conventional methods.
Why it matters
Potential benefit: If successful, the approach could reduce postoperative pain and improve patient comfort after root canal therapy.
How similar studies have gone: Previous work shows irrigation activation can improve cleanliness but may not always reduce pain, making this assessment important.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Inclusion Criteria Patients aged between 18 and 45 years. * Patients requiring primary root canal treatment. * Patients in good general health.. * Subjects classified as ASA-1 following the classification proposed by the American Society of Anesthesiologists. Exclusion Criteria: * Patients with systemic diseases affecting pain perception or healing. * Patients who had taken analgesics or antibiotics within 12-24 hours prior to treatment. * Pregnant or lactating women. * Previously treated teeth or teeth with root resorption, fractures, or severe periodontal disease. .
Where it's running
-
Endodontics Department Faculty of Dentistry
Minya, Egypt Recruiting
Study contacts
- Study coordinator: Nourhan Sayid Mohammed, B.D.S
- Email: Nourhansayid02@gmail.com
- Phone: +201097391219
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.