Neurodegenerative Diseases Registry
Official title: Biomarkers in Neurodegenerative Diseases
Run by Chinese University of Hong Kong · NCT04472130 · Data updated 2026-11-12
This registry collects data from adults with neurodegenerative conditions to help doctors distinguish between Parkinsonian syndromes and related disorders and understand disease progression over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 1400 (estimated) |
| Sponsor | Chinese University of Hong Kong Academic / other |
| Locations | 1 site (Hong Kong) |
| Status | Recruiting |
| Started | October 9, 2019 |
| Main results expected | August 1, 2031 |
| Study ends | August 1, 2031 |
| Registry record updated | September 18, 2026 |
| Trial ID | NCT04472130 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–80 with neurodegenerative diseases such as Parkinson disease, multiple system atrophy, or progressive supranuclear palsy who can participate in follow-up visits.
✕Probably not a fit
Individuals with conditions outside the specified parkinsonian syndromes or who cannot complete follow-up assessments may not derive direct personal benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational cohort study documents baseline and follow-up information on people with neurodegenerative diseases, including Parkinson disease, MSA, and PSP. Participants undergo standardized clinical assessments, questionnaires, and blood collection at baseline and at 1–2 year follow-ups, with additional eye-movement video recordings as needed. The goal is to improve differentiation among parkinsonian syndromes and track changes in function, cognition, and disease burden over time. Data will be collected across groups using disease-specific scales and common measures, enabling longitudinal analyses while adhering to standard follow-up intervals.
Why it matters
Potential benefit: Participants may contribute to a better understanding of disease trajectories and help improve future diagnostic accuracy and care for neurodegenerative conditions.
How similar studies have gone: Observational registries in neurodegenerative diseases have provided insights into progression and differential diagnosis, supporting the value of this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age should be between 18-80 years old. Exclusion Criteria: * Patients with ongoing central nervous system infection and/or acute stroke or active brain tumor.
Where it's running
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Chinese University of Hong Kong
Hong Kong, Hong Kong Recruiting
Study contacts
- Principal investigator: Vincent Mok, PhD — Chinese University of Hong Kong
- Study coordinator: Elyia Han, Bachelor
- Email: elyiahan@cuhk.edu.hk
- Phone: +852 2697 5027
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.