Registry and study on Helicobacter Pylori and related gastric conditions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to establish a registry to investigate the progression of pre-neoplastic lesions and gastric cancer associated with Helicobacter pylori infection. It will involve longitudinal data collection from adults diagnosed with H. pylori infection, atrophic gastritis, intestinal metaplasia, dysplasia, or gastric cancer. The study will utilize esophagogastroduodenoscopy for surveillance and data gathering to better understand the factors influencing disease progression and optimal surveillance techniques.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults \>= 18 years of age
* Written informed consent obtained
* Diagnosed with current or past H. pylori infection,
* Histologically proven atrophic gastritis (body and/or antrum of stomach), intestinal metaplasia (complete and incomplete), dysplasia (any grade) and/or gastric cancer (post- treatment)

Exclusion Criteria:

* Co-morbid illness that prohibit endoscopic surveillance
* Declines for study questionnaire, biobanking of specimens and/or regular review per study protocol

Where it's running

• Prince of Wales Hospital
  Hong Kong, Hong Kong Recruiting
• S.H. Ho Centre for Digestive Health, Prince of Wales Hospital
  Hong Kong, Hong Kong Recruiting

Study contacts

• Study coordinator: Andrew Ming Yeung HO
• Email: andrewho@cuhk.edu.hk
• Phone: 26371398

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Predicting gastric cancer risk in patients with intestinal metaplasia and atrophic gastritis

  This study is trying to find out which factors can help predict the risk of gastric cancer in patients who have intestinal metaplasia and atrophic gastritis.

  Recruiting Chinese University of Hong Kong · Shatin, New Territories · NCT04840056

• Monitoring patients with precursors to gastric cancer

  This study is testing the best ways to monitor people over 45 with early signs of stomach cancer to help keep them safe and healthy.

  Recruiting Instituto Portugues de Oncologia, Francisco Gentil, Porto · Porto · NCT04613570

• Prevalence and possible role of non-H. pylori Helicobacter species in gastric conditions and cancers

  Researchers will test stomach tissue from people with functional dyspeasia, various gastritis conditions, gastric cancer, and bariatric patients to see if non-H. pylori Helicobacter species are present.

  Recruiting at 3 sites Universiteit Antwerpen · Edegem and 2 other locations · NCT07770126

• H. pylori status and tissue features to predict gastric cancer behavior after endoscopic treatment

  This study tests whether current H. pylori infection status and tissue features can help predict how early gastric cancer will behave after endoscopic treatment.

  Recruiting at 3 sites Chinese PLA General Hospital · Beijing, Beijing Municipality and 2 other locations · NCT07724496

• Microplastic exposure and progression of stomach precancerous changes

  This project will test if adults with higher microplastic exposure are more likely to have precancerous stomach changes or gastric cancer.

  Recruiting Xijing Hospital of Digestive Diseases · Xi'an, Shaanxi · NCT07542652

• How autoimmune atrophic gastritis develops and presents over time

  This project will follow adults with autoimmune atrophic gastritis to see how the disease progresses and affects the stomach, nutrient absorption, and overall health.

  Recruiting Fondazione IRCCS Policlinico San Matteo di Pavia · Pavia, Pavia · NCT07388459

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.