Comparing Twice vs Thrice Weekly Hemodialysis for Elderly Patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of initiating hemodialysis treatment twice weekly versus the standard thrice weekly regimen in elderly patients with end-stage kidney disease (ESKD). The study aims to assess whether a less frequent dialysis schedule can reduce hospitalization rates and improve quality of life for frail elderly patients who may have multiple comorbidities. By focusing on patients with residual renal function, the trial seeks to validate a potentially safer and more effective approach to renal replacement therapy in this vulnerable population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥60 years
* Clinical diagnosis of end stage kidney disease
* Starting maintenance hemodialysis within one month
* 24-hour urine output ≥ 500 ml at randomization
* Sufficient understanding of the study procedures and requirements.

Exclusion Criteria:

* Left ventricular ejection fraction \< 40%)
* Liver cirrhosis
* Current treatment for an active malignancy or active infection
* Onability or refusal to provide written informed consent
* enrollment in another clinical trial.

Where it's running

• Soonchunhyang University Hospital Bucheon
  Bucheon-si, South Korea Recruiting
• Hallym University Medical Center- Chuncheon
  Chuncheon, South Korea Completed
• Soonchunhyang University Seoul Hospital
  Seoul, South Korea Active not recruiting
• Kangbuk Samsung Medical Center
  Seoul, South Korea Completed
• Koera University Guro Hospital
  Seoul, South Korea Completed
• The Catholic University of Korea, Yeouido St. Mary's Hospital
  Seoul, South Korea Completed

Study contacts

• Principal investigator: Soon Hyo Kwon, MD — Soonchunhyang University Hospital
• Study coordinator: Soon Hyo Kwon, MD
• Email: ksoonhyo@schmc.ac.kr
• Phone: +8227099177

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.