Postprandial drop and frailty in older adults having planned noncardiac surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study in adults aged 65+ undergoing elective noncardiac surgery with general anesthesia. It examines whether postprandial hypotension and frailty are linked to post-induction hypotension within the first 20 minutes after anesthesia or until incision. The study also explores whether the size of a meal-related blood pressure drop relates to subsequent blood pressure drops and the need for pressor medications. Data will be collected to identify if preoperative postprandial responses can serve as markers of anesthetic tolerance. No interventional treatment is implemented; findings aim to inform risk stratification and perioperative management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 65 years or older
* Scheduled for elective noncardiac surgery
* Scheduled to receive general anesthesia
* ASA physical status I-III
* Sufficient cognitive and communication ability to complete the Edmonton Frail Scale assessment
* Written informed consent

Exclusion Criteria:

* Emergency surgery
* Active bleeding or hemodynamic instability
* Vasopressor or inotropic support before induction
* No oral intake on the evening before surgery (e.g., nasogastric decompression, ileus, full bowel preparation)
* Permanent pacemaker or implanted device suppressing chronotropic response
* Atrial fibrillation or other arrhythmias impairing the reliability of oscillometric blood pressure measurement

Where it's running

• Konya City Hospital
  Konya, Konya, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Asiye Özkan Kaya — Konya City Hospital
• Study coordinator: Asiye Özkan Kaya, MD
• Email: asiyenur_94@hotmail.com
• Phone: +90 538 929 03 03

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.